Advances and Applications of Single-Cell Sequencing Technologies

Yong Wang; Nicholas E. Navin

doi:10.1016/j.molcel.2015.05.005

Advances and Applications of Single-Cell Sequencing Technologies

Yong Wang, Nicholas E. Navin

Research output: Contribution to journal › Review article › peer-review

416 Scopus citations

Abstract

Single-cell sequencing (SCS) has emerged as a powerful new set of technologies for studying rare cells and delineating complex populations. Over the past 5 years, SCS methods for DNA and RNA have had a broad impact on many diverse fields of biology, including microbiology, neurobiology, development, tissue mosaicism, immunology, and cancer research. In this review, we will discuss SCS technologies and applications, as well as translational applications in the clinic.

Original language	English (US)
Pages (from-to)	598-609
Number of pages	12
Journal	Molecular cell
Volume	58
Issue number	4
DOIs	https://doi.org/10.1016/j.molcel.2015.05.005
State	Published - May 21 2015

ASJC Scopus subject areas

Molecular Biology
Cell Biology

Access to Document

10.1016/j.molcel.2015.05.005

Cite this

@article{f751282b72cd4671920277622c479d58,

title = "Advances and Applications of Single-Cell Sequencing Technologies",

abstract = "Single-cell sequencing (SCS) has emerged as a powerful new set of technologies for studying rare cells and delineating complex populations. Over the past 5 years, SCS methods for DNA and RNA have had a broad impact on many diverse fields of biology, including microbiology, neurobiology, development, tissue mosaicism, immunology, and cancer research. In this review, we will discuss SCS technologies and applications, as well as translational applications in the clinic.",

author = "Yong Wang and Navin, {Nicholas E.}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = may,

day = "21",

doi = "10.1016/j.molcel.2015.05.005",

language = "English (US)",

volume = "58",

pages = "598--609",

journal = "Molecular cell",

issn = "1097-2765",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - Advances and Applications of Single-Cell Sequencing Technologies

AU - Wang, Yong

AU - Navin, Nicholas E.

PY - 2015/5/21

Y1 - 2015/5/21

N2 - Single-cell sequencing (SCS) has emerged as a powerful new set of technologies for studying rare cells and delineating complex populations. Over the past 5 years, SCS methods for DNA and RNA have had a broad impact on many diverse fields of biology, including microbiology, neurobiology, development, tissue mosaicism, immunology, and cancer research. In this review, we will discuss SCS technologies and applications, as well as translational applications in the clinic.

AB - Single-cell sequencing (SCS) has emerged as a powerful new set of technologies for studying rare cells and delineating complex populations. Over the past 5 years, SCS methods for DNA and RNA have had a broad impact on many diverse fields of biology, including microbiology, neurobiology, development, tissue mosaicism, immunology, and cancer research. In this review, we will discuss SCS technologies and applications, as well as translational applications in the clinic.

UR - http://www.scopus.com/inward/record.url?scp=84929661801&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929661801&partnerID=8YFLogxK

U2 - 10.1016/j.molcel.2015.05.005

DO - 10.1016/j.molcel.2015.05.005

M3 - Review article

C2 - 26000845

AN - SCOPUS:84929661801

SN - 1097-2765

VL - 58

SP - 598

EP - 609

JO - Molecular cell

JF - Molecular cell

IS - 4

ER -

Advances and Applications of Single-Cell Sequencing Technologies

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this