Advances in MRI-Based Assessment of Rectal Cancer Post-Neoadjuvant Therapy: A Comprehensive Review

Joao Miranda, Pamela Causa Andrieu, Josip Nincevic, Lucas de Padua Gomes de Farias, Hala Khasawneh, Yuki Arita, Nir Stanietzky, Maria Clara Fernandes, Tiago Biachi De Castria, Natally Horvat

Research output: Contribution to journalReview articlepeer-review

Abstract

Rectal cancer presents significant diagnostic and therapeutic challenges, with neoadjuvant therapy playing a pivotal role in improving resectability and patient outcomes. MRI serves as a critical tool in assessing treatment response. However, differentiating viable tumor tissue from therapy-induced changes on MRI remains a complex task. In this comprehensive review, we explore treatment options for rectal cancer based on resectability status, focusing on the role of MRI in guiding therapeutic decisions. We delve into the nuances of MRI-based evaluation of treatment response following neoadjuvant therapy, paying particular attention to emerging techniques like radiomics. Drawing from our insights based on the literature, we provide essential recommendations for post-neoadjuvant therapy management of rectal cancer, all within the context of MRI-based findings.

Original languageEnglish (US)
Article number172
JournalJournal of Clinical Medicine
Volume13
Issue number1
DOIs
StatePublished - Jan 2024

Keywords

  • magnetic resonance imaging
  • neoadjuvant therapy
  • rectal cancer
  • treatment response

ASJC Scopus subject areas

  • General Medicine

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