Advances in radiation treatments of breast cancer

Steven J. Frank, Marsha D. McNeese, Eric A. Strom, George Perkins, Mohammad Salehpour, Naomi Schechter, Thomas A. Buchholz

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

During the past decade, improvements in treatment-planning tools, computer and imaging technologies, and new therapeutic modalities have allowed radiation to be delivered in a conformal fashion while minimizing treatment toxicity. It is important that physicians involved in breast cancer treatment recognize the numerous advances that have occurred in the delivery of radiation therapy. Changes in 3 specific areas in treatment planning and delivery have revolutionized the way we approach breast cancer treatment: the design of radiation fields using computed tomographyt (CT) data sets, the development of 3-dimensional dose-calculation algorithms, and the development of new methods to modulate the delivery of radiation dose. With the advent of CT simulators, individual patient anatomy and pathology can be readily visualized and reconstructed in axial, coronal, and sagittal views. With an improved anatomic delineation between the target volumes and critical organ structures, the treatment fields can be designed to be more congruous to the areas at highest risk. In the past few years, new 3-dimensional dose-calculation algorithms have been generated that more accurately calculate dose distributions throughout the treatment-planning volume. Finally, modern linear accelerators allow for modulation of the dose intensity of the radiation beam, which may lead to improved aesthetics and decreased side effects while ensuring that the volumes at high receive the prescribed dose. Radiation therapy can be delivered safety and effectively to patients with breast cancer.

Original languageEnglish (US)
Pages (from-to)401-406
Number of pages6
JournalClinical breast cancer
Volume4
Issue number6
DOIs
StatePublished - Feb 2004

Keywords

  • Computed tomography
  • Dose intensity
  • Dose-calculation algorithms
  • Linear acceleration
  • Radiation beam
  • Target volume

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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