African American and Asian males: what do we know about germline predisposition to prostate cancer

There is a paucity of data related to highly penetrant genes associated with a genetic predisposition to prostate cancer or its virulence among men of diverse ancestral populations including African American and Asian men. We review the recent published literature to gain insights into whether such genetic alterations previously described among Caucasians are noted among African American and Asian prostate cancer patients.