ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: Does it matter for oncogenesis?

Francesco Turturro; Michael Driscoll; Ellen Friday; Tomas Welbourne

doi:10.3324/haematol.10923

ALK-mediated Na⁺/H⁺ exchanger-dependent intracellular alkalinization: Does it matter for oncogenesis?

Francesco Turturro, Michael Driscoll, Ellen Friday, Tomas Welbourne

Lymphoma-Myeloma

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In this study we investigated the relevance of the oncogenic protein NPM-ALK in regulating cellular pH (pHi) through the modulation of Na ⁺/H⁺ exchanger 1 (NHE1)-activity and the consequences of pHi pharmacological manipulation in cells expressing NPM-ALK.

Original language	English (US)
Pages (from-to)	706-707
Number of pages	2
Journal	Haematologica
Volume	92
Issue number	5
DOIs	https://doi.org/10.3324/haematol.10923
State	Published - May 2007

Keywords

ALCL
ALK
NHE1
Troglitazone

ASJC Scopus subject areas

Hematology

Access to Document

10.3324/haematol.10923

Cite this

@article{b3417f5e202d47fa96619e7f2d6dbfdf,

title = "ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: Does it matter for oncogenesis?",

abstract = "In this study we investigated the relevance of the oncogenic protein NPM-ALK in regulating cellular pH (pHi) through the modulation of Na +/H+ exchanger 1 (NHE1)-activity and the consequences of pHi pharmacological manipulation in cells expressing NPM-ALK.",

keywords = "ALCL, ALK, NHE1, Troglitazone",

author = "Francesco Turturro and Michael Driscoll and Ellen Friday and Tomas Welbourne",

year = "2007",

month = may,

doi = "10.3324/haematol.10923",

language = "English (US)",

volume = "92",

pages = "706--707",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

number = "5",

}

TY - JOUR

T1 - ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization

T2 - Does it matter for oncogenesis?

AU - Turturro, Francesco

AU - Driscoll, Michael

AU - Friday, Ellen

AU - Welbourne, Tomas

PY - 2007/5

Y1 - 2007/5

N2 - In this study we investigated the relevance of the oncogenic protein NPM-ALK in regulating cellular pH (pHi) through the modulation of Na +/H+ exchanger 1 (NHE1)-activity and the consequences of pHi pharmacological manipulation in cells expressing NPM-ALK.

AB - In this study we investigated the relevance of the oncogenic protein NPM-ALK in regulating cellular pH (pHi) through the modulation of Na +/H+ exchanger 1 (NHE1)-activity and the consequences of pHi pharmacological manipulation in cells expressing NPM-ALK.

KW - ALCL

KW - ALK

KW - NHE1

KW - Troglitazone

UR - http://www.scopus.com/inward/record.url?scp=34447295148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34447295148&partnerID=8YFLogxK

U2 - 10.3324/haematol.10923

DO - 10.3324/haematol.10923

M3 - Article

C2 - 17488701

AN - SCOPUS:34447295148

SN - 0390-6078

VL - 92

SP - 706

EP - 707

JO - Haematologica

JF - Haematologica

IS - 5

ER -