Abstract
Experiments were performed to determine the effect of neonatal estrogen treatment on the expression of the proto-oncogene c-fos in the BALB/c mouse cervicovaginal tract. Estradiol induces the expression of c-fos in the normal mouse cervicovaginal tract. However, c-fos expression was not stimulated by estradiol in the cervicovaginal tracts of mice that received neonatal estrogen treatment. In addition, the level of expression of c-fos by the estrogen- and progesterone-induced murine cervicovaginal LJ6195 tumor was similar to that in the normal vaginal tract following estradiol stimulation and was not regulated by estradiol.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2251-2253 |
| Number of pages | 3 |
| Journal | Endocrinology |
| Volume | 129 |
| Issue number | 4 |
| State | Published - Oct 1991 |
ASJC Scopus subject areas
- Endocrinology