An ultrastructural comparison of grade I and II endometrial adenocarcinoma considering estrogen and progesterone receptor status

D. V. Horbelt; R. S. Freedman; D. K. Roberts; N. J. Walker; C. L. Edwards; L. A. Jones

doi:10.1016/0090-8258(84)90022-2

An ultrastructural comparison of grade I and II endometrial adenocarcinoma considering estrogen and progesterone receptor status

D. V. Horbelt, R. S. Freedman, D. K. Roberts, N. J. Walker, C. L. Edwards, L. A. Jones

Health Disparities Research

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Eighteen (18) previously untreated patients with grade I (9) and II (9) endometrial adenocarcinoma provided endometrial samples for biochemical analysis of estrogen and progesterone receptors. The same samples were evaluated by histology and ultrastructure. Progesterone receptor negative samples (PR < 1000 fmole/g tissue) showed more ultrastructural characteristics of malignancy and a wider range of changes than the progesterone positive specimens (PR > 1000 fmole/g tissue). These findings appeared to be independent of estrogen receptor status. No significant ultrastructural changes were seen when grades I and II were compared.

Original language	English (US)
Pages (from-to)	150-156
Number of pages	7
Journal	Gynecologic oncology
Volume	18
Issue number	2
DOIs	https://doi.org/10.1016/0090-8258(84)90022-2
State	Published - Jun 1984

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

Access to Document

10.1016/0090-8258(84)90022-2

Cite this

@article{fc1a21ffca4c430f90f29d213fb6085a,

title = "An ultrastructural comparison of grade I and II endometrial adenocarcinoma considering estrogen and progesterone receptor status",

abstract = "Eighteen (18) previously untreated patients with grade I (9) and II (9) endometrial adenocarcinoma provided endometrial samples for biochemical analysis of estrogen and progesterone receptors. The same samples were evaluated by histology and ultrastructure. Progesterone receptor negative samples (PR < 1000 fmole/g tissue) showed more ultrastructural characteristics of malignancy and a wider range of changes than the progesterone positive specimens (PR > 1000 fmole/g tissue). These findings appeared to be independent of estrogen receptor status. No significant ultrastructural changes were seen when grades I and II were compared.",

author = "Horbelt, {D. V.} and Freedman, {R. S.} and Roberts, {D. K.} and Walker, {N. J.} and Edwards, {C. L.} and Jones, {L. A.}",

note = "Funding Information: {\textquoteright} Supported in part by a cancer research grant from the Ladies Auxiliary to the Veterans of Foreign Wars, Department of Kansas, and in part from the UpJohn Company. {\textquoteright} To whom reprint requests should be addressed: Department of Obstetrics and Gynecology, 550 North Hillside, Wichita, Kans. 67214.",

year = "1984",

month = jun,

doi = "10.1016/0090-8258(84)90022-2",

language = "English (US)",

volume = "18",

pages = "150--156",

journal = "Gynecologic oncology",

issn = "0090-8258",

publisher = "Academic Press Inc.",

number = "2",

}

TY - JOUR

T1 - An ultrastructural comparison of grade I and II endometrial adenocarcinoma considering estrogen and progesterone receptor status

AU - Horbelt, D. V.

AU - Freedman, R. S.

AU - Roberts, D. K.

AU - Walker, N. J.

AU - Edwards, C. L.

AU - Jones, L. A.

N1 - Funding Information: ’ Supported in part by a cancer research grant from the Ladies Auxiliary to the Veterans of Foreign Wars, Department of Kansas, and in part from the UpJohn Company. ’ To whom reprint requests should be addressed: Department of Obstetrics and Gynecology, 550 North Hillside, Wichita, Kans. 67214.

PY - 1984/6

Y1 - 1984/6

N2 - Eighteen (18) previously untreated patients with grade I (9) and II (9) endometrial adenocarcinoma provided endometrial samples for biochemical analysis of estrogen and progesterone receptors. The same samples were evaluated by histology and ultrastructure. Progesterone receptor negative samples (PR < 1000 fmole/g tissue) showed more ultrastructural characteristics of malignancy and a wider range of changes than the progesterone positive specimens (PR > 1000 fmole/g tissue). These findings appeared to be independent of estrogen receptor status. No significant ultrastructural changes were seen when grades I and II were compared.

AB - Eighteen (18) previously untreated patients with grade I (9) and II (9) endometrial adenocarcinoma provided endometrial samples for biochemical analysis of estrogen and progesterone receptors. The same samples were evaluated by histology and ultrastructure. Progesterone receptor negative samples (PR < 1000 fmole/g tissue) showed more ultrastructural characteristics of malignancy and a wider range of changes than the progesterone positive specimens (PR > 1000 fmole/g tissue). These findings appeared to be independent of estrogen receptor status. No significant ultrastructural changes were seen when grades I and II were compared.

UR - http://www.scopus.com/inward/record.url?scp=0021154904&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021154904&partnerID=8YFLogxK

U2 - 10.1016/0090-8258(84)90022-2

DO - 10.1016/0090-8258(84)90022-2

M3 - Article

C2 - 6735260

AN - SCOPUS:0021154904

SN - 0090-8258

VL - 18

SP - 150

EP - 156

JO - Gynecologic oncology

JF - Gynecologic oncology

IS - 2

ER -

An ultrastructural comparison of grade I and II endometrial adenocarcinoma considering estrogen and progesterone receptor status

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this