Analysis of gene expression profile in lung adenosquamous carcinoma using cDNA microarray

Fei Yang; Jiong Yang; Man Jiang; Bo Ye; Yu Xia Zhang; Hong Lei Chen; Dong Xia; Ming Qiu Liu

doi:10.1007/bf02850810

Analysis of gene expression profile in lung adenosquamous carcinoma using cDNA microarray

Fei Yang, Jiong Yang, Man Jiang, Bo Ye, Yu Xia Zhang, Hong Lei Chen, Dong Xia, Ming Qiu Liu

Translational Molecular Pathology

Research output: Contribution to journal › Article › peer-review

Abstract

Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4 096 human genes. Among target genes, 508 differentially expressed genes were identified in adenosqua-mous carcinoma of the lung, 232 genes were overexpressed and 276 genes were underexpressed. Among them, 92 genes are cell signals transduction genes, 34 genes are proto-onco-genes and tumor suppressor genes or cell cycle related genes or cell apoptosis related genes, 29 genes are cell skeleton genes, 28 genes are DNA synthesis, repair and recombination genes, 12 genes are DNA binding and transcription genes. These genes may be associated with the occurence and development of adenosquamous carinome of the lung.

Original language	English (US)
Pages (from-to)	967-972
Number of pages	6
Journal	Wuhan University Journal of Natural Sciences
Volume	9
Issue number	6
DOIs	https://doi.org/10.1007/bf02850810
State	Published - Nov 2004

Keywords

Adenosquamous carcinoma
Gene expression profile
Lung carcinoma
Microarray

ASJC Scopus subject areas

General

Access to Document

10.1007/bf02850810

Cite this

@article{9ba25de9c9b14196a9256432399dbc74,

title = "Analysis of gene expression profile in lung adenosquamous carcinoma using cDNA microarray",

abstract = "Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4 096 human genes. Among target genes, 508 differentially expressed genes were identified in adenosqua-mous carcinoma of the lung, 232 genes were overexpressed and 276 genes were underexpressed. Among them, 92 genes are cell signals transduction genes, 34 genes are proto-onco-genes and tumor suppressor genes or cell cycle related genes or cell apoptosis related genes, 29 genes are cell skeleton genes, 28 genes are DNA synthesis, repair and recombination genes, 12 genes are DNA binding and transcription genes. These genes may be associated with the occurence and development of adenosquamous carinome of the lung.",

keywords = "Adenosquamous carcinoma, Gene expression profile, Lung carcinoma, Microarray",

author = "Fei Yang and Jiong Yang and Man Jiang and Bo Ye and Zhang, {Yu Xia} and Chen, {Hong Lei} and Dong Xia and Liu, {Ming Qiu}",

note = "Funding Information: Received date: 2004-02-28 Foundation item: Supported by the National Natural Science Foundation of China (39870305) Biography= YANG Fei(1972-), female, Ph. D candidate, research direction: etiology and pathogenesis of lung cancer. E-mail= yangfei72 @ hotmail, corn 1{"} To whom correspondence should be addressed. E-maih yangfei72 @ hotmaiL con",

year = "2004",

month = nov,

doi = "10.1007/bf02850810",

language = "English (US)",

volume = "9",

pages = "967--972",

journal = "Wuhan University Journal of Natural Sciences",

issn = "1007-1202",

publisher = "Wuhan University",

number = "6",

}

TY - JOUR

T1 - Analysis of gene expression profile in lung adenosquamous carcinoma using cDNA microarray

AU - Yang, Fei

AU - Yang, Jiong

AU - Jiang, Man

AU - Ye, Bo

AU - Zhang, Yu Xia

AU - Chen, Hong Lei

AU - Xia, Dong

AU - Liu, Ming Qiu

N1 - Funding Information: Received date: 2004-02-28 Foundation item: Supported by the National Natural Science Foundation of China (39870305) Biography= YANG Fei(1972-), female, Ph. D candidate, research direction: etiology and pathogenesis of lung cancer. E-mail= yangfei72 @ hotmail, corn 1" To whom correspondence should be addressed. E-maih yangfei72 @ hotmaiL con

PY - 2004/11

Y1 - 2004/11

N2 - Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4 096 human genes. Among target genes, 508 differentially expressed genes were identified in adenosqua-mous carcinoma of the lung, 232 genes were overexpressed and 276 genes were underexpressed. Among them, 92 genes are cell signals transduction genes, 34 genes are proto-onco-genes and tumor suppressor genes or cell cycle related genes or cell apoptosis related genes, 29 genes are cell skeleton genes, 28 genes are DNA synthesis, repair and recombination genes, 12 genes are DNA binding and transcription genes. These genes may be associated with the occurence and development of adenosquamous carinome of the lung.

AB - Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4 096 human genes. Among target genes, 508 differentially expressed genes were identified in adenosqua-mous carcinoma of the lung, 232 genes were overexpressed and 276 genes were underexpressed. Among them, 92 genes are cell signals transduction genes, 34 genes are proto-onco-genes and tumor suppressor genes or cell cycle related genes or cell apoptosis related genes, 29 genes are cell skeleton genes, 28 genes are DNA synthesis, repair and recombination genes, 12 genes are DNA binding and transcription genes. These genes may be associated with the occurence and development of adenosquamous carinome of the lung.

KW - Adenosquamous carcinoma

KW - Gene expression profile

KW - Lung carcinoma

KW - Microarray

UR - http://www.scopus.com/inward/record.url?scp=11144229796&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=11144229796&partnerID=8YFLogxK

U2 - 10.1007/bf02850810

DO - 10.1007/bf02850810

M3 - Article

AN - SCOPUS:11144229796

SN - 1007-1202

VL - 9

SP - 967

EP - 972

JO - Wuhan University Journal of Natural Sciences

JF - Wuhan University Journal of Natural Sciences

IS - 6

ER -

Analysis of gene expression profile in lung adenosquamous carcinoma using cDNA microarray

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this