Abstract
Chlamydia trachomatis is a Gram-negative eubacterium with a dimorphic developmental cycle and obligate intracellular growth in the eucaryotic host. The Dam transmethylase of Escherichia coli methylates at the N6 position of adenine in the sequence 5′-GATC-3′ and the Dcm transmethylase adds methyl groups to the C5 position of the internal cytosines in the sequences 5′-CCWGG-3′. In contrast to E. coli, C. trachomatis DNA appears to have unmethylated Dam sites and only low level Dcm methylation.
Original language | English (US) |
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Pages (from-to) | 161-168 |
Number of pages | 8 |
Journal | FEMS Microbiology Letters |
Volume | 98 |
Issue number | 1-3 |
DOIs | |
State | Published - Nov 1 1992 |
Keywords
- Chlamydia trachomatis
- Dam transmethylase
- Dcm transmethylase
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
- Genetics