Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization

Seiji Isonishi; Robert L. Coleman; Masanori Hirama; Yasushi Iida; Satomi Kitai; Masanori Nagase; Kazuhiko Ochiai

doi:10.1016/j.ajog.2007.09.026

Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization

Seiji Isonishi, Robert L. Coleman, Masanori Hirama, Yasushi Iida, Satomi Kitai, Masanori Nagase, Kazuhiko Ochiai

Gynecological Oncology & Reproductive Medicine

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Objective: The objective of the study was to describe a clinically useful factors index predicting long-term efficacy of uterine artery embolization (UAE). Study Design: Newly diagnosed patients with uterine leiomyoma wishing to retain their uterus underwent UAE at our institution. Clinical demographics and 4 prognostic factors were recovered from the medical record. A regrowth-free interval (RFI) was calculated for all patients based on leiomyoma regrowth or recurrence of any previously reported symptoms. RFI by prognostic factor was analyzed by the Kaplan-Meier method. Results: Forty-three patients were identified. Two prognostic factors were identified by multivariate analysis: vascularity (dichotomized as hypervascular vs hypovascular; RFI at 2 years, 80% vs 20%, P = .001) and number of nodules (solitary vs multiple; RFI at 2 years, 72% vs 25% at 2 years, P = .001). Conclusion: UAE success may be predicted by 2 preoperative parameters. Further investigation is warranted.

Original language	English (US)
Pages (from-to)	270.e1-270.e6
Journal	American journal of obstetrics and gynecology
Volume	198
Issue number	3
DOIs	https://doi.org/10.1016/j.ajog.2007.09.026
State	Published - Mar 2008

Keywords

embolization
leiomyoma
prognostic factor

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/j.ajog.2007.09.026

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title = "Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization",

abstract = "Objective: The objective of the study was to describe a clinically useful factors index predicting long-term efficacy of uterine artery embolization (UAE). Study Design: Newly diagnosed patients with uterine leiomyoma wishing to retain their uterus underwent UAE at our institution. Clinical demographics and 4 prognostic factors were recovered from the medical record. A regrowth-free interval (RFI) was calculated for all patients based on leiomyoma regrowth or recurrence of any previously reported symptoms. RFI by prognostic factor was analyzed by the Kaplan-Meier method. Results: Forty-three patients were identified. Two prognostic factors were identified by multivariate analysis: vascularity (dichotomized as hypervascular vs hypovascular; RFI at 2 years, 80% vs 20%, P = .001) and number of nodules (solitary vs multiple; RFI at 2 years, 72% vs 25% at 2 years, P = .001). Conclusion: UAE success may be predicted by 2 preoperative parameters. Further investigation is warranted.",

keywords = "embolization, leiomyoma, prognostic factor",

author = "Seiji Isonishi and Coleman, {Robert L.} and Masanori Hirama and Yasushi Iida and Satomi Kitai and Masanori Nagase and Kazuhiko Ochiai",

year = "2008",

month = mar,

doi = "10.1016/j.ajog.2007.09.026",

language = "English (US)",

volume = "198",

pages = "270.e1--270.e6",

journal = "American journal of obstetrics and gynecology",

issn = "0002-9378",

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T1 - Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization

AU - Isonishi, Seiji

AU - Coleman, Robert L.

AU - Hirama, Masanori

AU - Iida, Yasushi

AU - Kitai, Satomi

AU - Nagase, Masanori

AU - Ochiai, Kazuhiko

PY - 2008/3

Y1 - 2008/3

N2 - Objective: The objective of the study was to describe a clinically useful factors index predicting long-term efficacy of uterine artery embolization (UAE). Study Design: Newly diagnosed patients with uterine leiomyoma wishing to retain their uterus underwent UAE at our institution. Clinical demographics and 4 prognostic factors were recovered from the medical record. A regrowth-free interval (RFI) was calculated for all patients based on leiomyoma regrowth or recurrence of any previously reported symptoms. RFI by prognostic factor was analyzed by the Kaplan-Meier method. Results: Forty-three patients were identified. Two prognostic factors were identified by multivariate analysis: vascularity (dichotomized as hypervascular vs hypovascular; RFI at 2 years, 80% vs 20%, P = .001) and number of nodules (solitary vs multiple; RFI at 2 years, 72% vs 25% at 2 years, P = .001). Conclusion: UAE success may be predicted by 2 preoperative parameters. Further investigation is warranted.

AB - Objective: The objective of the study was to describe a clinically useful factors index predicting long-term efficacy of uterine artery embolization (UAE). Study Design: Newly diagnosed patients with uterine leiomyoma wishing to retain their uterus underwent UAE at our institution. Clinical demographics and 4 prognostic factors were recovered from the medical record. A regrowth-free interval (RFI) was calculated for all patients based on leiomyoma regrowth or recurrence of any previously reported symptoms. RFI by prognostic factor was analyzed by the Kaplan-Meier method. Results: Forty-three patients were identified. Two prognostic factors were identified by multivariate analysis: vascularity (dichotomized as hypervascular vs hypovascular; RFI at 2 years, 80% vs 20%, P = .001) and number of nodules (solitary vs multiple; RFI at 2 years, 72% vs 25% at 2 years, P = .001). Conclusion: UAE success may be predicted by 2 preoperative parameters. Further investigation is warranted.

KW - embolization

KW - leiomyoma

KW - prognostic factor

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SP - 270.e1-270.e6

JO - American journal of obstetrics and gynecology

JF - American journal of obstetrics and gynecology

IS - 3

ER -

Analysis of prognostic factors for patients with leiomyoma treated with uterine arterial embolization

Abstract

Keywords

ASJC Scopus subject areas

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