TY - JOUR
T1 - Anatomy and Breast Cancer Staging
T2 - Is It Still Relevant?
AU - Plichta, Jennifer K.
AU - Campbell, Brittany M.
AU - Mittendorf, Elizabeth A.
AU - Hwang, E. Shelley
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2018/1
Y1 - 2018/1
N2 - Breast cancer staging concisely summarizes disease status, creating a framework for assessing and relaying prognostic information. The fundamental concepts and components of breast cancer staging are reviewed. The AJCC Cancer Staging Manual, which includes traditional anatomic factors, now includes additional tumor characteristics: tumor grade, estrogen receptor status, progesterone receptor status, human epidermal growth factor receptor 2 status, and (when available) multigene panel testing from the primary tumor. With these updates, staging provides the most reliable system for accurately predicting patient outcome. When the AJCC 8th edition guidelines are adopted, they will more closely reflect tumor biology.
AB - Breast cancer staging concisely summarizes disease status, creating a framework for assessing and relaying prognostic information. The fundamental concepts and components of breast cancer staging are reviewed. The AJCC Cancer Staging Manual, which includes traditional anatomic factors, now includes additional tumor characteristics: tumor grade, estrogen receptor status, progesterone receptor status, human epidermal growth factor receptor 2 status, and (when available) multigene panel testing from the primary tumor. With these updates, staging provides the most reliable system for accurately predicting patient outcome. When the AJCC 8th edition guidelines are adopted, they will more closely reflect tumor biology.
KW - Biomarkers
KW - Breast cancer
KW - Prognosis
KW - Staging
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U2 - 10.1016/j.soc.2017.07.010
DO - 10.1016/j.soc.2017.07.010
M3 - Review article
C2 - 29132565
AN - SCOPUS:85034265375
SN - 1055-3207
VL - 27
SP - 51
EP - 67
JO - Surgical oncology clinics of North America
JF - Surgical oncology clinics of North America
IS - 1
ER -