TY - JOUR
T1 - Ankylosing spondylitis of juvenile onset
T2 - Comparison with adult onset disease
AU - García-Morteo, Osvaldo
AU - Maldonado-Cocco, José A.
AU - Suärez-Almazor, María E.
AU - Garay, Estela
PY - 1983
Y1 - 1983
N2 - Although less frequently, ankylosing spondylitis (AS) may also occur during childhood. The present report describes the clinical features in 24 patients with AS of juvenile onset and its comparison with those found in 71 patients with adult onset AS. A slightly increased prevalence of female patients was found in the juvenile onset group. Peripheral joint involvement as a mono- or oligo-articular arthritis was significantly more frequent in juvenile onset patients, not only as a mode of onset but also during the course of the disease. 5.4 years after onset all these patients had developed axial involvement. Extraarticular manifestations occurred with similar frequency in juvenile and adult onset patients. One juvenile patient had associated multiple sclerosis; one juvenile and one adult onset patient developed amyloidosis. Impairment of functional capacity was more severe in the juvenile onset group; hip joint involvement was closely related to a poorer prognosis.
AB - Although less frequently, ankylosing spondylitis (AS) may also occur during childhood. The present report describes the clinical features in 24 patients with AS of juvenile onset and its comparison with those found in 71 patients with adult onset AS. A slightly increased prevalence of female patients was found in the juvenile onset group. Peripheral joint involvement as a mono- or oligo-articular arthritis was significantly more frequent in juvenile onset patients, not only as a mode of onset but also during the course of the disease. 5.4 years after onset all these patients had developed axial involvement. Extraarticular manifestations occurred with similar frequency in juvenile and adult onset patients. One juvenile patient had associated multiple sclerosis; one juvenile and one adult onset patient developed amyloidosis. Impairment of functional capacity was more severe in the juvenile onset group; hip joint involvement was closely related to a poorer prognosis.
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U2 - 10.3109/03009748309098542
DO - 10.3109/03009748309098542
M3 - Article
C2 - 6623013
AN - SCOPUS:0020635026
SN - 0300-9742
VL - 12
SP - 246
EP - 248
JO - Scandinavian Journal of Rheumatology
JF - Scandinavian Journal of Rheumatology
IS - 3
ER -