Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway

Medicine & Life Sciences

• Trastuzumab 100%
• Phosphatidylinositol 3-Kinases 83%
• Histones 78%
• Anti-Idiotypic Antibodies 70%
• Cyclin E 35%
• Cyclin A 18%
• Phosphotransferases 16%
• Cyclin D1 15%
• Breast Neoplasms 13%
• Up-Regulation 10%
• Phosphorylation 9%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 8%
• DNA 7%
• G1 Phase 7%
• Northern Blotting 6%
• S Phase 6%
• Molecular Weight 5%
• Real-Time Polymerase Chain Reaction 5%
• Cell Cycle 5%
• Proteins 5%
• Down-Regulation 4%
• Therapeutics 4%
• Gene Expression 4%
• Messenger RNA 4%