Aprindine hepatitis

H. F. Herlong; P. R. Reid; J. K. Boitnott; W. C. Maddrey

doi:10.7326/0003-4819-89-3-359

Aprindine hepatitis

H. F. Herlong, P. R. Reid, J. K. Boitnott, W. C. Maddrey

Gastroenterology Hepatology & Nutrition

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16 Scopus citations

Abstract

We have seen two patients whose hepatitis was due to the administration of aprindine, a new antiarrhythmic agent. In both patients evidence of hepatitis appeared within 3 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. The reintroduction of aprindine in one patient was associated with the reappearance of hepatitis, which resolved despite continued administration of the drug.

Original language	English (US)
Pages (from-to)	359-361
Number of pages	3
Journal	Annals of internal medicine
Volume	89
Issue number	3
DOIs	https://doi.org/10.7326/0003-4819-89-3-359
State	Published - 1978

ASJC Scopus subject areas

Internal Medicine

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10.7326/0003-4819-89-3-359

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title = "Aprindine hepatitis",

abstract = "We have seen two patients whose hepatitis was due to the administration of aprindine, a new antiarrhythmic agent. In both patients evidence of hepatitis appeared within 3 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. The reintroduction of aprindine in one patient was associated with the reappearance of hepatitis, which resolved despite continued administration of the drug.",

author = "Herlong, {H. F.} and Reid, {P. R.} and Boitnott, {J. K.} and Maddrey, {W. C.}",

year = "1978",

doi = "10.7326/0003-4819-89-3-359",

language = "English (US)",

volume = "89",

pages = "359--361",

journal = "Annals of internal medicine",

issn = "0003-4819",

publisher = "American College of Physicians",

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T1 - Aprindine hepatitis

AU - Herlong, H. F.

AU - Reid, P. R.

AU - Boitnott, J. K.

AU - Maddrey, W. C.

PY - 1978

Y1 - 1978

N2 - We have seen two patients whose hepatitis was due to the administration of aprindine, a new antiarrhythmic agent. In both patients evidence of hepatitis appeared within 3 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. The reintroduction of aprindine in one patient was associated with the reappearance of hepatitis, which resolved despite continued administration of the drug.

AB - We have seen two patients whose hepatitis was due to the administration of aprindine, a new antiarrhythmic agent. In both patients evidence of hepatitis appeared within 3 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. The reintroduction of aprindine in one patient was associated with the reappearance of hepatitis, which resolved despite continued administration of the drug.

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U2 - 10.7326/0003-4819-89-3-359

DO - 10.7326/0003-4819-89-3-359

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VL - 89

SP - 359

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JO - Annals of internal medicine

JF - Annals of internal medicine

IS - 3

ER -

Aprindine hepatitis

Abstract

ASJC Scopus subject areas

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