TY - JOUR
T1 - Arsenic exposure and oral cavity lesions in Bangladesh
AU - Syed, Emdadul H.
AU - Melkonian, Stephanie
AU - Poudel, Krishna C.
AU - Yasuoka, Junko
AU - Otsuka, Keiko
AU - Ahmed, Alauddin
AU - Islam, Tariqul
AU - Parvez, Faruque
AU - Slavkovich, Vesna
AU - Graziano, Joseph H.
AU - Ahsan, Habibul
AU - Jimba, Masamine
PY - 2013/1
Y1 - 2013/1
N2 - OBJECTIVE:: To evaluate the relationship between arsenic exposure and oral cavity lesions among an arsenic-exposed population in Bangladesh. METHODS:: We carried out an analysis utilizing the baseline data of the Health Effects of Arsenic Exposure Longitudinal Study, which is an ongoing population-based cohort study to investigate health outcomes associated with arsenic exposure via drinking water in Araihazar, Bangladesh. We used multinomial regression models to estimate the risk of oral cavity lesions. RESULTS:: Participants with high urinary arsenic levels (286.1 to 5000.0 μg/g) were more likely to develop arsenical lesions of the gums (multinomial odds ratio = 2.90; 95% confidence interval, 1.11 to 7.54), and tongue (multinomial odds ratio = 2.79; 95% confidence interval, 1.51 to 5.15), compared with those with urinary arsenic levels of 7.0 to 134.0 μg/g. CONCLUSIONS:: Higher level of arsenic exposure was positively associated with increased arsenical lesions of the gums and tongue.
AB - OBJECTIVE:: To evaluate the relationship between arsenic exposure and oral cavity lesions among an arsenic-exposed population in Bangladesh. METHODS:: We carried out an analysis utilizing the baseline data of the Health Effects of Arsenic Exposure Longitudinal Study, which is an ongoing population-based cohort study to investigate health outcomes associated with arsenic exposure via drinking water in Araihazar, Bangladesh. We used multinomial regression models to estimate the risk of oral cavity lesions. RESULTS:: Participants with high urinary arsenic levels (286.1 to 5000.0 μg/g) were more likely to develop arsenical lesions of the gums (multinomial odds ratio = 2.90; 95% confidence interval, 1.11 to 7.54), and tongue (multinomial odds ratio = 2.79; 95% confidence interval, 1.51 to 5.15), compared with those with urinary arsenic levels of 7.0 to 134.0 μg/g. CONCLUSIONS:: Higher level of arsenic exposure was positively associated with increased arsenical lesions of the gums and tongue.
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U2 - 10.1097/JOM.0b013e31826bb686
DO - 10.1097/JOM.0b013e31826bb686
M3 - Article
C2 - 23201591
AN - SCOPUS:84873088089
SN - 1076-2752
VL - 55
SP - 59
EP - 66
JO - Journal of occupational and environmental medicine
JF - Journal of occupational and environmental medicine
IS - 1
ER -