TY - JOUR
T1 - Assessment of the 10-year risk of cardiovascular events among a group of Sub-Saharan African post-menopausal women
AU - Ama Moor, Vicky Jocelyne
AU - Nansseu, Jobert Richie N.
AU - Nouaga, Murielle Elsa D.
AU - Noubiap, Jean Jacques N.
AU - Nguetsa, Guylaine D.
AU - Tchanana, Gladys
AU - Ketcha, Arthur
AU - Fokom-Domgue, Joël
N1 - Publisher Copyright:
© 2016 Via Medica.
PY - 2016
Y1 - 2016
N2 - Background: Post-menopausal women may be at particular risk of developing cardiovascular disease due to metabolic changes occurring at menopause. The present study aimed assess the 10-year cardiovascular risk (CVR) among a group of post-menopausal women and determine associated factors. Methods: This was a cross-sectional study conducted among post-menopausal women in Yaoundé, Cameroon. CVR was calculated using the Framingham risk score. Results: We enrolled 108 women, their ages ranging from 45 to 80 years, with a mean of 56.4 ± ± 6.9 years. CVR ranged between 1.2 and was greater than 30% with a mean of 13.4 ± 8.7%. Forty-three (39.8%) participants had a low CVR (< 10%), 39 (36.1%) women had a moderate CVR (10-20%), and 21 (24.1%) women had a high CVR (> 20%). Low-density lipoproteins cholesterol (LDL-C; b = 3.27, p = 0.004), fasting plasma glucose (b = 5.40, p = 0.015), and diastolic blood pressure (DBP; b = 3.49, p < 0.0001) were independently associated with CVR. Women not married (i.e. single, divorced or widowed) (adjusted odds ratio [aOR] 4.66, p = 0.002), those with high titers of LDL-C (≥ 1.6 g/L; aOR 5.07, p = 0.001), and those with elevated DBP (≥ 90 mm Hg; aOR 8.10, p < 0.0001) presented an increased likelihood to be at an advanced level of CVR. Conclusions: A significant number of post-menopausal women are at considerable risk of cardiovascular events in our setting. Therefore, they should be educated to adopt healthy lifestyles for substantial reduction in their CVR.
AB - Background: Post-menopausal women may be at particular risk of developing cardiovascular disease due to metabolic changes occurring at menopause. The present study aimed assess the 10-year cardiovascular risk (CVR) among a group of post-menopausal women and determine associated factors. Methods: This was a cross-sectional study conducted among post-menopausal women in Yaoundé, Cameroon. CVR was calculated using the Framingham risk score. Results: We enrolled 108 women, their ages ranging from 45 to 80 years, with a mean of 56.4 ± ± 6.9 years. CVR ranged between 1.2 and was greater than 30% with a mean of 13.4 ± 8.7%. Forty-three (39.8%) participants had a low CVR (< 10%), 39 (36.1%) women had a moderate CVR (10-20%), and 21 (24.1%) women had a high CVR (> 20%). Low-density lipoproteins cholesterol (LDL-C; b = 3.27, p = 0.004), fasting plasma glucose (b = 5.40, p = 0.015), and diastolic blood pressure (DBP; b = 3.49, p < 0.0001) were independently associated with CVR. Women not married (i.e. single, divorced or widowed) (adjusted odds ratio [aOR] 4.66, p = 0.002), those with high titers of LDL-C (≥ 1.6 g/L; aOR 5.07, p = 0.001), and those with elevated DBP (≥ 90 mm Hg; aOR 8.10, p < 0.0001) presented an increased likelihood to be at an advanced level of CVR. Conclusions: A significant number of post-menopausal women are at considerable risk of cardiovascular events in our setting. Therefore, they should be educated to adopt healthy lifestyles for substantial reduction in their CVR.
KW - Cameroon
KW - Cardiovascular disease
KW - Cardiovascular risk
KW - Post-menopausal women
KW - Sub-Saharan Africa
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U2 - 10.5603/CJ.a2015.0056
DO - 10.5603/CJ.a2015.0056
M3 - Article
C2 - 26412602
AN - SCOPUS:84964757064
SN - 1897-5593
VL - 23
SP - 123
EP - 131
JO - Cardiology Journal
JF - Cardiology Journal
IS - 2
ER -