TY - JOUR
T1 - Association between changes in having of cancer patients in the family and depression
T2 - A longitudinal panel study
AU - Jang, Yun Seo
AU - Yoon, Na Young
AU - Hurh, Kyungduk
AU - Park, Eun Cheol
AU - Ha, Min Jin
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2023/7/15
Y1 - 2023/7/15
N2 - Background: Cancer diagnosis can cause considerable stress among patients and their families. Both may experience clinical depression and severe anxiety. Therefore, this study investigated the association between the occurrence of cancer patients in the family and the depression among family members. Methods: Data from the Korean Longitudinal Study of Aging (2006–2020) were used. A total of 6251 participants who completed the short-form Center for Epidemiologic Studies Depression Scale (CESD-10-D) questionnaire were included. General estimating equations were used to assess the temporal effects of changes on depression in the presence of cancer patients in the family. Results: Having cancer patients in the family was associated with a high risk of depression among both men and women (men, Odds Ratio (OR):1.78, 95 % Confidence Intervals (CI) 1.13–2.79; women, OR:1.53, 95 % CI 1.06–2.22). Depressive symptoms were particularly high in women, especially when cancer symptoms were more severe than previous surveys (OR: 2.48, 95 % CI 1.18–5.20). Limitations: First, non-responders were excluded but this could be affected by underestimation bias. Second, depression was defined as the CESD-10-D score, and the biological risk factors of depression could not be identified because of survey-based database. Third, due to the retrospective design study, confirming the causal relationship clearly is difficult. Finally, residual scheming effects of unmeasured variables could not be eliminated. Conclusion: Our findings support efforts to diagnose and manage depression in the families of cancer patients. Accordingly, healthcare services and supportive interventions to reduce the psychological factors of cancer patients' families are needed.
AB - Background: Cancer diagnosis can cause considerable stress among patients and their families. Both may experience clinical depression and severe anxiety. Therefore, this study investigated the association between the occurrence of cancer patients in the family and the depression among family members. Methods: Data from the Korean Longitudinal Study of Aging (2006–2020) were used. A total of 6251 participants who completed the short-form Center for Epidemiologic Studies Depression Scale (CESD-10-D) questionnaire were included. General estimating equations were used to assess the temporal effects of changes on depression in the presence of cancer patients in the family. Results: Having cancer patients in the family was associated with a high risk of depression among both men and women (men, Odds Ratio (OR):1.78, 95 % Confidence Intervals (CI) 1.13–2.79; women, OR:1.53, 95 % CI 1.06–2.22). Depressive symptoms were particularly high in women, especially when cancer symptoms were more severe than previous surveys (OR: 2.48, 95 % CI 1.18–5.20). Limitations: First, non-responders were excluded but this could be affected by underestimation bias. Second, depression was defined as the CESD-10-D score, and the biological risk factors of depression could not be identified because of survey-based database. Third, due to the retrospective design study, confirming the causal relationship clearly is difficult. Finally, residual scheming effects of unmeasured variables could not be eliminated. Conclusion: Our findings support efforts to diagnose and manage depression in the families of cancer patients. Accordingly, healthcare services and supportive interventions to reduce the psychological factors of cancer patients' families are needed.
KW - Cancer
KW - Depression
KW - Family
KW - Psychiatry
KW - Psycho-oncology
KW - Support
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U2 - 10.1016/j.jad.2023.04.095
DO - 10.1016/j.jad.2023.04.095
M3 - Article
C2 - 37119866
AN - SCOPUS:85153797174
SN - 0165-0327
VL - 333
SP - 482
EP - 488
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -