Author’s view: Radiation and immunotherapy as systemic therapy for solid tumors

Steven N. Seyedin; Chad Tang; James W. Welsh

doi:10.4161/2162402X.2014.986402

Author’s view: Radiation and immunotherapy as systemic therapy for solid tumors

Steven N. Seyedin, Chad Tang, James W. Welsh

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.

Original language	English (US)
Pages (from-to)	1-3
Number of pages	3
Journal	OncoImmunology
Volume	4
Issue number	3
DOIs	https://doi.org/10.4161/2162402X.2014.986402
State	Published - 2015

Keywords

Abscopal effect
Antibodies
CTLA4
Immune checkpoint inhibitors
PD1
PDL1
Radiation therapy

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Oncology

Access to Document

10.4161/2162402X.2014.986402

Cite this

@article{f9e47fa074f440bcbc7ea49ba88f9eb7,

title = "Author{\textquoteright}s view: Radiation and immunotherapy as systemic therapy for solid tumors",

abstract = "The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.",

keywords = "Abscopal effect, Antibodies, CTLA4, Immune checkpoint inhibitors, PD1, PDL1, Radiation therapy",

author = "Seyedin, {Steven N.} and Chad Tang and Welsh, {James W.}",

note = "Publisher Copyright: {\textcopyright} 2015 Taylor & Francis Group, LLC.",

year = "2015",

doi = "10.4161/2162402X.2014.986402",

language = "English (US)",

volume = "4",

pages = "1--3",

journal = "OncoImmunology",

issn = "2162-4011",

publisher = "Landes Bioscience",

number = "3",

}

TY - JOUR

T1 - Author’s view

T2 - Radiation and immunotherapy as systemic therapy for solid tumors

AU - Seyedin, Steven N.

AU - Tang, Chad

AU - Welsh, James W.

PY - 2015

Y1 - 2015

N2 - The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.

AB - The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.

KW - Abscopal effect

KW - Antibodies

KW - CTLA4

KW - Immune checkpoint inhibitors

KW - PD1

KW - PDL1

KW - Radiation therapy

UR - http://www.scopus.com/inward/record.url?scp=84954466729&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84954466729&partnerID=8YFLogxK

U2 - 10.4161/2162402X.2014.986402

DO - 10.4161/2162402X.2014.986402

M3 - Article

C2 - 25949899

AN - SCOPUS:84954466729

SN - 2162-4011

VL - 4

SP - 1

EP - 3

JO - OncoImmunology

JF - OncoImmunology

IS - 3

ER -

Author’s view: Radiation and immunotherapy as systemic therapy for solid tumors

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this