Autonomic function after botulinum toxin type A or B: A double-blind, randomized trial

Ron Tintner; R. Gross; U. F. Winzer; K. A. Smalky; J. Jankovic

doi:10.1212/01.wnl.0000174433.76707.8c

Autonomic function after botulinum toxin type A or B: A double-blind, randomized trial

Ron Tintner, R. Gross, U. F. Winzer, K. A. Smalky, J. Jankovic

General Internal Medicine

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

To compare autonomic effects of botulinum toxin (BTX), we randomized patients with cervical dystonia to receive either BTX-A or BTX-B in a double-blind manner. Efficacy and physiologic questionnaire measures of autonomic function were assessed at baseline and 2 weeks after injection. Patients treated with BTX-B had less saliva production (p < 0.01) and greater severity of constipation (p = 0.037) than those treated with BTX-A, but did not differ in other tests of autonomic functions.

Original language	English (US)
Pages (from-to)	765-767
Number of pages	3
Journal	Neurology
Volume	65
Issue number	5
DOIs	https://doi.org/10.1212/01.wnl.0000174433.76707.8c
State	Published - Sep 13 2005

ASJC Scopus subject areas

Clinical Neurology

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abstract = "To compare autonomic effects of botulinum toxin (BTX), we randomized patients with cervical dystonia to receive either BTX-A or BTX-B in a double-blind manner. Efficacy and physiologic questionnaire measures of autonomic function were assessed at baseline and 2 weeks after injection. Patients treated with BTX-B had less saliva production (p < 0.01) and greater severity of constipation (p = 0.037) than those treated with BTX-A, but did not differ in other tests of autonomic functions.",

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AU - Smalky, K. A.

AU - Jankovic, J.

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AB - To compare autonomic effects of botulinum toxin (BTX), we randomized patients with cervical dystonia to receive either BTX-A or BTX-B in a double-blind manner. Efficacy and physiologic questionnaire measures of autonomic function were assessed at baseline and 2 weeks after injection. Patients treated with BTX-B had less saliva production (p < 0.01) and greater severity of constipation (p = 0.037) than those treated with BTX-A, but did not differ in other tests of autonomic functions.

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Autonomic function after botulinum toxin type A or B: A double-blind, randomized trial

Abstract

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