TY - JOUR
T1 - Bacterial and fungal infections in patients with the acquired immunodeficiency syndrome.
AU - Rolston, K. V.
AU - Radentz, S.
AU - Rodriguez, S.
N1 - Copyright:
Medline is the source for the citation and abstract of this record.
PY - 1990
Y1 - 1990
N2 - Over a 14-month period, 136 episodes of bacterial and 26 episodes of fungal infection were identified from the microbiology records of 444 patients with acquired immunodeficiency syndrome (AIDS). The respective rates for infection were 31 of 100 admissions (bacterial) and 5 of 100 admissions (fungal). Contributory factors appeared to be therapy with antineoplastic agents, ganciclovir and zidovudine, resulting in neutropenia, corticosteroid therapy, and increased use of central venous catheters. Bacteria isolated most often were Staphylococcus spp., the Enterobacteriaceae, and Pseudomonas aeruginosa. Aspergillus spp. and Candida spp. were the common fungal pathogens. However, several unusual fungal organisms seem to be emerging as important pathogens and can cause disseminated infection. Appropriate and prompt antimicrobial therapy resulted in the resolution of most bacterial infections. Disseminated fungal infections were difficult to treat and responded less often.
AB - Over a 14-month period, 136 episodes of bacterial and 26 episodes of fungal infection were identified from the microbiology records of 444 patients with acquired immunodeficiency syndrome (AIDS). The respective rates for infection were 31 of 100 admissions (bacterial) and 5 of 100 admissions (fungal). Contributory factors appeared to be therapy with antineoplastic agents, ganciclovir and zidovudine, resulting in neutropenia, corticosteroid therapy, and increased use of central venous catheters. Bacteria isolated most often were Staphylococcus spp., the Enterobacteriaceae, and Pseudomonas aeruginosa. Aspergillus spp. and Candida spp. were the common fungal pathogens. However, several unusual fungal organisms seem to be emerging as important pathogens and can cause disseminated infection. Appropriate and prompt antimicrobial therapy resulted in the resolution of most bacterial infections. Disseminated fungal infections were difficult to treat and responded less often.
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M3 - Article
C2 - 2386975
AN - SCOPUS:0025179559
SN - 0361-090X
VL - 14
SP - 377
EP - 381
JO - Cancer Detection and Prevention
JF - Cancer Detection and Prevention
IS - 3
ER -