Abstract
Driving cancer cells into a more differentiated state is a rational therapeutic approach. Primary uveal melanoma cells with a propensity to metastasize have less-differentiated features than their less aggressive counterparts. Treatment of uveal melanoma cells with histone deacetylase inhibitors induces a more differentiated phenotype with resultant lower growth capacity.
Original language | English (US) |
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Pages (from-to) | 323-325 |
Number of pages | 3 |
Journal | Clinical Cancer Research |
Volume | 18 |
Issue number | 2 |
DOIs | |
State | Published - Jan 15 2012 |
ASJC Scopus subject areas
- Oncology
- Cancer Research