Barrett's esophagus: Treatments of adenocarcinomas II

William S. Twaddell, Peter C. Wu, Roy J.J. Verhage, Marcus Feith, David H. Ilson, Christoph P. Schuhmacher, James D. Luketich, Björn Brücher, Daniel Vallböhmer, Wayne L. Hofstetter, Mark Jonathan Krasna, Daniela Kandioler, Paul M. Schneider, Bas P.L. Wijnhoven, Stephen J. Sontag

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The following topics are explored in this collection of commentaries on treatments of adenocarcinomas related to Barrett's esophagus: the importance of intraoperative frozen sections of the margins for the detection of high dysplasia; the preferable way for sentinel node dissection; the current role of robotic surgery and of video-endoscopic approach; the value of the Siewert's classification of adenocarcinomas; the indications of two-step esophagectomy; the evaluation of pathological complete response; the role of PET scan in staging and response assessment; the role of p53 in the selection of adenocarcinomas patients; chemotherapy regimens for adenocarcinomas; the use of monoclonal antibodies in the control of cell proliferation; he attempt to define a stage-specific strategy, and the possible indications of selective therapy; and changes in mortality rates from esophageal cancer.

Original languageEnglish (US)
Pages (from-to)265-291
Number of pages27
JournalAnnals of the New York Academy of Sciences
Volume1232
Issue number1
DOIs
StatePublished - Sep 2011

Keywords

  • 5-FU
  • AEG
  • Adenocarcinoma
  • Adenovirus vector
  • Barrett's esophagus
  • Chemoradiation
  • Chemoradiotherapy
  • Cisplatin
  • EGFR
  • Esophageal cancer
  • FDG PET scan
  • FOLFOX
  • Gamma probe
  • Gefitinib
  • HER2
  • High risk patients
  • Integrated PET/CT scan
  • Lymphadenectomy
  • Minimally invasive esophagectomy
  • Molecular markers
  • Multimodality therapy
  • Neoadjuvant chemotherapy
  • P53
  • PET tracer
  • Prognosis
  • R0 resection
  • Radiotherapy
  • Residual disease
  • Robot assisted thoracolaparoscopic esophagectomy
  • Robotic surgery
  • Sentinel lymph nodes
  • Sentinel node
  • Siewert 's classification
  • Submucosal invasion
  • Two-stade esophagectomy

ASJC Scopus subject areas

  • General Neuroscience
  • General Biochemistry, Genetics and Molecular Biology
  • History and Philosophy of Science

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