Bayesian function-on-function regression for multilevel functional data

Mark J. Meyer, Brent A. Coull, Francesco Versace, Paul Cinciripini, Jeffrey S. Morris

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

Medical and public health research increasingly involves the collection of complex and high dimensional data. In particular, functional data-where the unit of observation is a curve or set of curves that are finely sampled over a grid-is frequently obtained. Moreover, researchers often sample multiple curves per person resulting in repeated functional measures. A common question is how to analyze the relationship between two functional variables. We propose a general function-on-function regression model for repeatedly sampled functional data on a fine grid, presenting a simple model as well as a more extensive mixed model framework, and introducing various functional Bayesian inferential procedures that account for multiple testing. We examine these models via simulation and a data analysis with data from a study that used event-related potentials to examine how the brain processes various types of images.

Original languageEnglish (US)
Pages (from-to)563-574
Number of pages12
JournalBiometrics
Volume71
Issue number3
DOIs
StatePublished - Sep 1 2015

Keywords

  • Basis functions
  • Bayesian inference
  • Function-on-function regression
  • Functional data analysis
  • Functional mixed models
  • Functional testing
  • Principal components
  • Wavelet regression

ASJC Scopus subject areas

  • Statistics and Probability
  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences
  • Applied Mathematics

MD Anderson CCSG core facilities

  • Biostatistics Resource Group

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