TY - JOUR
T1 - Biologic response modifiers in pediatric cancer
AU - Worth, Laura L.
AU - Jeha, Sima S.
AU - Kleinerman, Eugenie S.
PY - 2001
Y1 - 2001
N2 - Biologic response modifiers are becoming an important addition to surgery, chemotherapy, and radiotherapy in the management of cancer. As this field of research grows and expands, more biologic response modifiers will be incorporated into therapeutic regimens. By stimulating the immune system to eradicate minimal residual disease, these agents may improve the disease-free and long-term survival rates of patients with a variety of malignancies. The challenge is to incorporate biologic response modifiers into the treatment armamentarium in ways that will maximize their tumorigenicity.
AB - Biologic response modifiers are becoming an important addition to surgery, chemotherapy, and radiotherapy in the management of cancer. As this field of research grows and expands, more biologic response modifiers will be incorporated into therapeutic regimens. By stimulating the immune system to eradicate minimal residual disease, these agents may improve the disease-free and long-term survival rates of patients with a variety of malignancies. The challenge is to incorporate biologic response modifiers into the treatment armamentarium in ways that will maximize their tumorigenicity.
UR - http://www.scopus.com/inward/record.url?scp=0034793421&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034793421&partnerID=8YFLogxK
U2 - 10.1016/S0889-8588(05)70244-6
DO - 10.1016/S0889-8588(05)70244-6
M3 - Article
C2 - 11676281
AN - SCOPUS:0034793421
SN - 0889-8588
VL - 15
SP - 723
EP - 740
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
IS - 4
ER -