Biology-based combined-modality radiotherapy: Workshop report

Kathryn A. Mason; Ritsuko Komaki; James D. Cox; Luka Milas

doi:10.1016/S0360-3016(01)01554-1

Biology-based combined-modality radiotherapy: Workshop report

Kathryn A. Mason, Ritsuko Komaki, James D. Cox, Luka Milas

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Purpose: The purpose of this workshop summary is to provide an overview of preclinical and clinical data on combined-modality radiotherapy. Methods and Materials: The 8th Annual Radiation Workshop at Round Top was held April 13-16, 2000 at the International Festival Institute (Round Top, TX). Results: Presentations by 30 speakers (from Germany, Netherlands, Australia, England, and France along with U.S. participants and M. D. Anderson Cancer Center faculty) formed the framework for discussions on the current status and future perspectives of biology-based combined-modality radiotherapy. Conclusion: Cellular and molecular pathways available for radiation modification by chemical and biologic agents are numerous, providing new opportunities for translational research in radiation oncology and for more effective combined-modality treatment of cancer.

Original language	English (US)
Pages (from-to)	1079-1089
Number of pages	11
Journal	International Journal of Radiation Oncology Biology Physics
Volume	50
Issue number	4
DOIs	https://doi.org/10.1016/S0360-3016(01)01554-1
State	Published - Jul 15 2001

Keywords

Anti-androgenic agents
Blockade of ras Oncogenes
Chemotherapy
Combined-modality treatment
Cox-2 inhibitors
Cytokines
Growth factors
Radioprotectors
Radiotherapy

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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title = "Biology-based combined-modality radiotherapy: Workshop report",

abstract = "Purpose: The purpose of this workshop summary is to provide an overview of preclinical and clinical data on combined-modality radiotherapy. Methods and Materials: The 8th Annual Radiation Workshop at Round Top was held April 13-16, 2000 at the International Festival Institute (Round Top, TX). Results: Presentations by 30 speakers (from Germany, Netherlands, Australia, England, and France along with U.S. participants and M. D. Anderson Cancer Center faculty) formed the framework for discussions on the current status and future perspectives of biology-based combined-modality radiotherapy. Conclusion: Cellular and molecular pathways available for radiation modification by chemical and biologic agents are numerous, providing new opportunities for translational research in radiation oncology and for more effective combined-modality treatment of cancer.",

keywords = "Anti-androgenic agents, Blockade of ras Oncogenes, Chemotherapy, Combined-modality treatment, Cox-2 inhibitors, Cytokines, Growth factors, Radioprotectors, Radiotherapy",

author = "Mason, {Kathryn A.} and Ritsuko Komaki and Cox, {James D.} and Luka Milas",

note = "Funding Information: This meeting was supported by the Stringer Chair (James D. Cox, Division of Radiation Oncology, M. D. Anderson Cancer Center), United Energy Resources, Inc., Professorship of Cancer Research (Luka Milas, Department of Experimental Radiation Oncology, M. D. Anderson Cancer Center), and the Helen Buchanan and Stanley Joseph Seeger Research Professorship (Howard D. Thames, Department of Biomathematics, M. D. Anderson Cancer Center).",

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doi = "10.1016/S0360-3016(01)01554-1",

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AU - Komaki, Ritsuko

AU - Cox, James D.

AU - Milas, Luka

N1 - Funding Information: This meeting was supported by the Stringer Chair (James D. Cox, Division of Radiation Oncology, M. D. Anderson Cancer Center), United Energy Resources, Inc., Professorship of Cancer Research (Luka Milas, Department of Experimental Radiation Oncology, M. D. Anderson Cancer Center), and the Helen Buchanan and Stanley Joseph Seeger Research Professorship (Howard D. Thames, Department of Biomathematics, M. D. Anderson Cancer Center).

PY - 2001/7/15

Y1 - 2001/7/15

N2 - Purpose: The purpose of this workshop summary is to provide an overview of preclinical and clinical data on combined-modality radiotherapy. Methods and Materials: The 8th Annual Radiation Workshop at Round Top was held April 13-16, 2000 at the International Festival Institute (Round Top, TX). Results: Presentations by 30 speakers (from Germany, Netherlands, Australia, England, and France along with U.S. participants and M. D. Anderson Cancer Center faculty) formed the framework for discussions on the current status and future perspectives of biology-based combined-modality radiotherapy. Conclusion: Cellular and molecular pathways available for radiation modification by chemical and biologic agents are numerous, providing new opportunities for translational research in radiation oncology and for more effective combined-modality treatment of cancer.

AB - Purpose: The purpose of this workshop summary is to provide an overview of preclinical and clinical data on combined-modality radiotherapy. Methods and Materials: The 8th Annual Radiation Workshop at Round Top was held April 13-16, 2000 at the International Festival Institute (Round Top, TX). Results: Presentations by 30 speakers (from Germany, Netherlands, Australia, England, and France along with U.S. participants and M. D. Anderson Cancer Center faculty) formed the framework for discussions on the current status and future perspectives of biology-based combined-modality radiotherapy. Conclusion: Cellular and molecular pathways available for radiation modification by chemical and biologic agents are numerous, providing new opportunities for translational research in radiation oncology and for more effective combined-modality treatment of cancer.

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KW - Blockade of ras Oncogenes

KW - Chemotherapy

KW - Combined-modality treatment

KW - Cox-2 inhibitors

KW - Cytokines

KW - Growth factors

KW - Radioprotectors

KW - Radiotherapy

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Biology-based combined-modality radiotherapy: Workshop report

Abstract

Keywords

ASJC Scopus subject areas

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