TY - JOUR
T1 - Biopsies of non-small cell lung cancer
T2 - central review in cooperative studies of the Radiation Therapy Oncology Group.
AU - Yesner, R.
AU - Seydel, G. H.
AU - Asbell, S. O.
AU - Cox, J. D.
AU - Bauer, M.
AU - Shin, K. H.
AU - Byhardt, R.
AU - Perez, C.
PY - 1991/7
Y1 - 1991/7
N2 - Cooperative trials involving many institutions have long been recognized as a major means of gaining enough experience in a reasonably short period of time to determine the effectiveness of new approaches in cancer therapy. In order to make such multiinstitutional trials meaningful, it is necessary to have uniform and objective diagnostic standards in histopathology. Large cooperative therapeutic trials, such as the Radiation Therapy Oncology Group (RTOG) constructs, must rely on the histopathologic diagnoses of many pathologists from varied institutions or subject them to central review, which is a longer and costlier process. This study is an assay of the need for central review in cooperative studies on non-small cell lung cancer, which includes squamous cell, large cell, adenocarcinomas, and combined squamous cell and adenocarcinomas.
AB - Cooperative trials involving many institutions have long been recognized as a major means of gaining enough experience in a reasonably short period of time to determine the effectiveness of new approaches in cancer therapy. In order to make such multiinstitutional trials meaningful, it is necessary to have uniform and objective diagnostic standards in histopathology. Large cooperative therapeutic trials, such as the Radiation Therapy Oncology Group (RTOG) constructs, must rely on the histopathologic diagnoses of many pathologists from varied institutions or subject them to central review, which is a longer and costlier process. This study is an assay of the need for central review in cooperative studies on non-small cell lung cancer, which includes squamous cell, large cell, adenocarcinomas, and combined squamous cell and adenocarcinomas.
UR - http://www.scopus.com/inward/record.url?scp=0026199238&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026199238&partnerID=8YFLogxK
M3 - Review article
C2 - 1656431
AN - SCOPUS:0026199238
SN - 0893-3952
VL - 4
SP - 432
EP - 435
JO - Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
JF - Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
IS - 4
ER -