TY - JOUR
T1 - Biospecimen repositories and cytopathology
AU - Krishnamurthy, Savitri
N1 - Publisher Copyright:
© 2014 American Cancer Society.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Biospecimen repositories are important for the advancement of biomedical research. Literature on the potential for biobanking of fine-needle aspiration, gynecologic, and nongynecologic cytology specimens is very limited. The potential for biobanking of these specimens as valuable additional resources to surgically excised tissues appears to be excellent. The cervicovaginal specimens that can be used for biobanking include Papanicolaou-stained monolayer preparations and residual material from liquid-based cytology preparations. Different types of specimen preparations of fine-needle aspiration and nongynecologic specimens, including Papanicolaou-stained and Diff-Quik-stained smears, cell blocks. and dedicated passes/residual material from fine-needle aspiration stored frozen in a variety of solutions, can be used for biobanking. Because of several gaps in knowledge regarding the standard of operative procedures for the procurement, storage, and quality assessment of cytology specimens, further studies as well as national conferences and workshops are needed not only to create awareness but also to facilitate the use of cytopathology specimens for biobanking.
AB - Biospecimen repositories are important for the advancement of biomedical research. Literature on the potential for biobanking of fine-needle aspiration, gynecologic, and nongynecologic cytology specimens is very limited. The potential for biobanking of these specimens as valuable additional resources to surgically excised tissues appears to be excellent. The cervicovaginal specimens that can be used for biobanking include Papanicolaou-stained monolayer preparations and residual material from liquid-based cytology preparations. Different types of specimen preparations of fine-needle aspiration and nongynecologic specimens, including Papanicolaou-stained and Diff-Quik-stained smears, cell blocks. and dedicated passes/residual material from fine-needle aspiration stored frozen in a variety of solutions, can be used for biobanking. Because of several gaps in knowledge regarding the standard of operative procedures for the procurement, storage, and quality assessment of cytology specimens, further studies as well as national conferences and workshops are needed not only to create awareness but also to facilitate the use of cytopathology specimens for biobanking.
KW - biobanking
KW - cytopathology
KW - fine-needle aspiration
KW - gynecologic specimens
UR - http://www.scopus.com/inward/record.url?scp=84929133018&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929133018&partnerID=8YFLogxK
U2 - 10.1002/cncy.21505
DO - 10.1002/cncy.21505
M3 - Review article
C2 - 25524469
AN - SCOPUS:84929133018
SN - 1934-662X
VL - 123
SP - 152
EP - 161
JO - Cancer Cytopathology
JF - Cancer Cytopathology
IS - 3
ER -