TY - JOUR
T1 - Blood pressure and symptoms of depression and anxiety
T2 - A prospective study
AU - Shinn, Eileen Huh
AU - Poston, Walker S.Carlos
AU - Kimball, Kay T.
AU - St. Jeor, Sachiko T.
AU - Foreyt, John P.
N1 - Funding Information:
This work was supported by grants from the National Heart, Lung, and Blood Institute (HL34589), National Cancer Institute (2-R25-CA57712; R-25-CA57730), and a Minority Scientist Development Award from the American Heart Association and with funds contributed by the AHA, Puerto Rico Affiliate.
PY - 2001
Y1 - 2001
N2 - This study investigated whether symptoms of depression and anxiety were related to the development of elevated blood presure in initially normotensive adults. The study's hypothesis was addressed with an existing set of prospective data gathered from an age-, sex-, and weight-stratified sample of 508 adults. Four years of follow-up data were analyzed both with logistic analysis, which used hypertension (blood presssure ≥ 140 mm Hg systolic or 90 mm Hg diastolic) as the dependent variable, and with multiple regression analysis, which used change in blood pressure as the dependent variable. Five physical risk factors for hypertension (age, sex, baseline body mass index, family history of hypertension, and baseline blood pressure levels) were controlled for in the regression analyses. Use of antidepressant/antianxiety and antihypertensive medications were controlled for in the study. Of the 433 normotensive participants who were eligible for our study, 15% had missing data in the logistic regression analysis focusing on depression (n = 371); similarly, 15% of the eligible sample had missing data in the logistic regression using anxiety as the psychological variable of interest (n = 370). Both logistic regression analyses showed no significant relationship for either depression or anxiety in the development of hypertension. The multiple regression analyses (n = 369 for the depression analysis; n = 361 for the anxiety analysis) similarly showed no relationship between either depression or anxiety in changes in blood pressure during the 4-year follow-up. Thus, our results do not support the role of depressive or anxiety symptoms in the development of hypertension in our sample of initially normotensive adults.
AB - This study investigated whether symptoms of depression and anxiety were related to the development of elevated blood presure in initially normotensive adults. The study's hypothesis was addressed with an existing set of prospective data gathered from an age-, sex-, and weight-stratified sample of 508 adults. Four years of follow-up data were analyzed both with logistic analysis, which used hypertension (blood presssure ≥ 140 mm Hg systolic or 90 mm Hg diastolic) as the dependent variable, and with multiple regression analysis, which used change in blood pressure as the dependent variable. Five physical risk factors for hypertension (age, sex, baseline body mass index, family history of hypertension, and baseline blood pressure levels) were controlled for in the regression analyses. Use of antidepressant/antianxiety and antihypertensive medications were controlled for in the study. Of the 433 normotensive participants who were eligible for our study, 15% had missing data in the logistic regression analysis focusing on depression (n = 371); similarly, 15% of the eligible sample had missing data in the logistic regression using anxiety as the psychological variable of interest (n = 370). Both logistic regression analyses showed no significant relationship for either depression or anxiety in the development of hypertension. The multiple regression analyses (n = 369 for the depression analysis; n = 361 for the anxiety analysis) similarly showed no relationship between either depression or anxiety in changes in blood pressure during the 4-year follow-up. Thus, our results do not support the role of depressive or anxiety symptoms in the development of hypertension in our sample of initially normotensive adults.
KW - Anxiety
KW - Depression
KW - Psychosocial risk factors for hypertension
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U2 - 10.1016/S0895-7061(01)01304-8
DO - 10.1016/S0895-7061(01)01304-8
M3 - Article
C2 - 11482304
AN - SCOPUS:0034952321
SN - 0895-7061
VL - 14
SP - 660
EP - 664
JO - American journal of hypertension
JF - American journal of hypertension
IS - 7 I
ER -