Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites

Jungsil Ro; Jae Y. Ro; Adel El-Naggar; Frankie A. Holmes; David Close; Gabriel N. Hortobagyi

Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites

Jungsil Ro, Jae Y. Ro, Adel El-Naggar, Frankie A. Holmes, David Close, Gabriel N. Hortobagyi

Pathology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T₁, N_o) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.

Original language	English (US)
Pages (from-to)	35-38
Number of pages	4
Journal	Breast Disease
Volume	3
Issue number	1
State	Published - May 1990

Keywords

DNA flow cytometry
breast cancer
metastatic brain tumor

ASJC Scopus subject areas

Oncology
Cancer Research

Cite this

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title = "Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites",

abstract = "The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T1, No) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.",

keywords = "DNA flow cytometry, breast cancer, metastatic brain tumor",

author = "Jungsil Ro and Ro, {Jae Y.} and Adel El-Naggar and Holmes, {Frankie A.} and David Close and Hortobagyi, {Gabriel N.}",

year = "1990",

month = may,

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T1 - Brain metastasis initial presentation of breast cancer

T2 - DNA flow cytometric comparison of two sites

AU - Ro, Jungsil

AU - Ro, Jae Y.

AU - El-Naggar, Adel

AU - Holmes, Frankie A.

AU - Close, David

AU - Hortobagyi, Gabriel N.

PY - 1990/5

Y1 - 1990/5

N2 - The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T1, No) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.

AB - The case of a metastatic brain tumor that antedated the diagnosis of a small primary breast cancer (T1, No) by 2 months in a 38-year-old woman is reported. DNA flow cytometry showed similar clonal populations for the primary and metastatic tumors, but the metastatic site had a larger aneuploid population and a higher S-phase fraction. This unusual presentation may be explained by the faster tumor growth rate of the metastatic site as determined by DNA flow cytometry.

KW - DNA flow cytometry

KW - breast cancer

KW - metastatic brain tumor

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ER -

Brain metastasis initial presentation of breast cancer: DNA flow cytometric comparison of two sites

Abstract

Keywords

ASJC Scopus subject areas

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