BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development

Agriculture & Biology

• neural crest 100%
• skeletal development 98%
• breast neoplasms 84%
• neoplasms 56%
• cells 23%
• bones 17%
• DNA damage 13%
• apoptosis 12%
• null alleles 8%
• mutants 7%
• mice 7%
• gene regulatory networks 7%
• stem cells 6%
• pathogenesis 6%
• niches 5%
• inactivation 5%

Medicine & Life Sciences

• Neural Crest 85%
• Bone Development 81%
• Breast Neoplasms 47%
• Craniofacial Abnormalities 31%
• Neoplasms 23%
• Bone and Bones 18%
• DNA Damage 18%
• Epithelial Cells 15%
• Multipotent Stem Cells 14%
• Apoptosis 12%
• Gene Regulatory Networks 11%
• Alleles 7%
• Survival 5%

Earth & Environmental Sciences

• tumor 77%
• cancer 68%
• bone 59%
• cell 45%
• defect 32%
• apoptosis 16%
• abnormality 13%
• mutant 12%
• malformation 7%
• damage 7%
• allele 6%
• niche 5%
• stem 5%
• gene 4%