Breast cancer biomarkers and molecular medicine: Part II

Jeffrey S. Ross; Gerald P. Linette; James Stec; Edwin Clark; Mark Ayers; Nick Leschly; W. Fraser Symmans; Gabriel N. Hortobagyi; Lajos Pusztai

doi:10.1586/14737159.4.2.169

Breast cancer biomarkers and molecular medicine: Part II

Jeffrey S. Ross, Gerald P. Linette, James Stec, Edwin Clark, Mark Ayers, Nick Leschly, W. Fraser Symmans, Gabriel N. Hortobagyi, Lajos Pusztai

Pathology

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

In this second part of the two-part review of breast cancer biomarkers and molecular medicine, the first section will consider additional breast cancer prognostic factors, Including oncogenes, tumor suppressor genes, cell adhesion molecules, Invasion-associated proteins and proteases, hormone receptor proteins, drug resistance proteins, apoptosis regulators, transcription factors, telomerase, DNA repair and methylation and transcriptional profiling using high-density genomic microarrays. The second section will consider the prediction of therapy response using the techniques of pharmacogenetics and pharmacogenomics.

Original language	English (US)
Pages (from-to)	169-188
Number of pages	20
Journal	Expert Review of Molecular Diagnostics
Volume	4
Issue number	2
DOIs	https://doi.org/10.1586/14737159.4.2.169
State	Published - Mar 2004

Keywords

Biomarkers
Breast cancer
ER
Heat shock proteins
MDR
Matrix metalloproteases
Microarrays
Oncogenes
P53
PR proteases
Pharmacogenetics
Pharmacogenomics
Plasminogen
Prognosis
Telomerase
Transcriptional profiling
Tumor suppressor genes

ASJC Scopus subject areas

Pathology and Forensic Medicine
Molecular Medicine
Molecular Biology
Genetics

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10.1586/14737159.4.2.169

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@article{a0d67893251f403ea34baee1b50f0805,

title = "Breast cancer biomarkers and molecular medicine: Part II",

abstract = "In this second part of the two-part review of breast cancer biomarkers and molecular medicine, the first section will consider additional breast cancer prognostic factors, Including oncogenes, tumor suppressor genes, cell adhesion molecules, Invasion-associated proteins and proteases, hormone receptor proteins, drug resistance proteins, apoptosis regulators, transcription factors, telomerase, DNA repair and methylation and transcriptional profiling using high-density genomic microarrays. The second section will consider the prediction of therapy response using the techniques of pharmacogenetics and pharmacogenomics.",

keywords = "Biomarkers, Breast cancer, ER, Heat shock proteins, MDR, Matrix metalloproteases, Microarrays, Oncogenes, P53, PR proteases, Pharmacogenetics, Pharmacogenomics, Plasminogen, Prognosis, Telomerase, Transcriptional profiling, Tumor suppressor genes",

author = "Ross, {Jeffrey S.} and Linette, {Gerald P.} and James Stec and Edwin Clark and Mark Ayers and Nick Leschly and Symmans, {W. Fraser} and Hortobagyi, {Gabriel N.} and Lajos Pusztai",

note = "Funding Information: This work was supported in part by the National Institutes of Health through MD Anderson{\textquoteright}s Cancer Center Support Grant [CA016672].",

year = "2004",

month = mar,

doi = "10.1586/14737159.4.2.169",

language = "English (US)",

volume = "4",

pages = "169--188",

journal = "Expert Review of Molecular Diagnostics",

issn = "1473-7159",

publisher = "Expert Reviews Ltd.",

number = "2",

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TY - JOUR

T1 - Breast cancer biomarkers and molecular medicine

T2 - Part II

AU - Ross, Jeffrey S.

AU - Linette, Gerald P.

AU - Stec, James

AU - Clark, Edwin

AU - Ayers, Mark

AU - Leschly, Nick

AU - Symmans, W. Fraser

AU - Hortobagyi, Gabriel N.

AU - Pusztai, Lajos

N1 - Funding Information: This work was supported in part by the National Institutes of Health through MD Anderson’s Cancer Center Support Grant [CA016672].

PY - 2004/3

Y1 - 2004/3

N2 - In this second part of the two-part review of breast cancer biomarkers and molecular medicine, the first section will consider additional breast cancer prognostic factors, Including oncogenes, tumor suppressor genes, cell adhesion molecules, Invasion-associated proteins and proteases, hormone receptor proteins, drug resistance proteins, apoptosis regulators, transcription factors, telomerase, DNA repair and methylation and transcriptional profiling using high-density genomic microarrays. The second section will consider the prediction of therapy response using the techniques of pharmacogenetics and pharmacogenomics.

AB - In this second part of the two-part review of breast cancer biomarkers and molecular medicine, the first section will consider additional breast cancer prognostic factors, Including oncogenes, tumor suppressor genes, cell adhesion molecules, Invasion-associated proteins and proteases, hormone receptor proteins, drug resistance proteins, apoptosis regulators, transcription factors, telomerase, DNA repair and methylation and transcriptional profiling using high-density genomic microarrays. The second section will consider the prediction of therapy response using the techniques of pharmacogenetics and pharmacogenomics.

KW - Biomarkers

KW - Breast cancer

KW - ER

KW - Heat shock proteins

KW - MDR

KW - Matrix metalloproteases

KW - Microarrays

KW - Oncogenes

KW - P53

KW - PR proteases

KW - Pharmacogenetics

KW - Pharmacogenomics

KW - Plasminogen

KW - Prognosis

KW - Telomerase

KW - Transcriptional profiling

KW - Tumor suppressor genes

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DO - 10.1586/14737159.4.2.169

M3 - Review article

C2 - 14995904

AN - SCOPUS:1542358118

SN - 1473-7159

VL - 4

SP - 169

EP - 188

JO - Expert Review of Molecular Diagnostics

JF - Expert Review of Molecular Diagnostics

IS - 2

ER -

Breast cancer biomarkers and molecular medicine: Part II

Abstract

Keywords

ASJC Scopus subject areas

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