Abstract
Most men with breast cancer present with a mass in the breast, the evaluation of which should include a tissue diagnosis. If the presence of invasive cancer is established, adequate local therapy includes total removal of the breast. Most tumors are hormone-receptor positive. In high-risk patients, the use of endocrine adjuvant therapy and/or combined endocrine and chemotherapy should be considered. Patients with estrogen-receptor (ER)-negative disease should be offered chemotherapy. In patients with metastatic disease and ER-positive tumors, initial treatment should be endocrine therapy; systemic chemotherapy should be used in patients who are either hormone-receptor negative or resistant to available endocrine therapies.
Original language | English (US) |
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Pages (from-to) | 1361-1364 |
Number of pages | 4 |
Journal | ONCOLOGY |
Volume | 17 |
Issue number | 10 |
State | Published - Oct 2003 |
ASJC Scopus subject areas
- Oncology
- Cancer Research