Breast Implant–Associated Anaplastic Large Cell Lymphoma: Defining Future Research Priorities

Ryan C. DeCoster, Evan B. Lynch, Alisha R. Bonaroti, Roberto N. Miranda, Kelly K. Hunt, Mark W. Clemens

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) is an emerging cancer of the immune system that is exclusively associated with textured-surface breast implants. This clinical review provides an update on the diagnosis and management of BIA-ALCL with an emphasis on major advances. The epidemiology and pathophysiology of the disease are also reviewed, focusing on current paradigm shifts and highlighting current controversies related to disease classification and risk mitigation. Finally, the authors conclude by discussing medicolegal and ethical issues surrounding BIA-ALCL while establishing a future basic science and clinical research agenda that is central to improving patient safety.

Original languageEnglish (US)
Pages (from-to)33-43
Number of pages11
JournalClinics in Plastic Surgery
Volume48
Issue number1
DOIs
StatePublished - Jan 2021

Keywords

  • BIA-ALCL
  • Breast implants
  • Lymphoma

ASJC Scopus subject areas

  • Surgery

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