Busting robustness: Using cancer's greatest strength to our advantage

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

What do complex networks, such as those found in cancer cells, airplane flight patterns and the Internet have in common? A remarkable robustness with a surprising vulnerability. Complex networks follow remarkably similar patterns across seemingly unconnected fields, and it is possible that cancer researchers could thus learn from the advances in complex network theory. Very limited, yet coordinated, specific targeting of the most critical parts of a network can have dramatically outsized effects. "At times, our strengths propel us so far forward we can no longer endure our weaknesses and perish from them." Nietzsche</italic.

Original languageEnglish (US)
Pages (from-to)73-77
Number of pages5
JournalFuture Oncology
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2015

Keywords

  • Cancer
  • combination therapy
  • complexity
  • robustness
  • scale free networks
  • small molecule inhibitors
  • targeted therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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