Abstract
What do complex networks, such as those found in cancer cells, airplane flight patterns and the Internet have in common? A remarkable robustness with a surprising vulnerability. Complex networks follow remarkably similar patterns across seemingly unconnected fields, and it is possible that cancer researchers could thus learn from the advances in complex network theory. Very limited, yet coordinated, specific targeting of the most critical parts of a network can have dramatically outsized effects. "At times, our strengths propel us so far forward we can no longer endure our weaknesses and perish from them." Nietzsche</italic.
Original language | English (US) |
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Pages (from-to) | 73-77 |
Number of pages | 5 |
Journal | Future Oncology |
Volume | 11 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2015 |
Keywords
- Cancer
- combination therapy
- complexity
- robustness
- scale free networks
- small molecule inhibitors
- targeted therapy
ASJC Scopus subject areas
- Oncology
- Cancer Research