CA 125: A clinically useful tumor marker in the management of colorectal carcinoma metastatic to the liver in patients with normal carcinoembryonic antigen

Giora M. Mavligit; Zeev Estrov; Aman U. Buzdar; Christine F. Wogan

doi:10.1097/00000421-200004000-00021

CA 125: A clinically useful tumor marker in the management of colorectal carcinoma metastatic to the liver in patients with normal carcinoembryonic antigen

Giora M. Mavligit, Zeev Estrov, Aman U. Buzdar, Christine F. Wogan

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7 Scopus citations

Abstract

Two patients with colon carcinoma metastatic to the liver had normal plasma carcinoembryonic antigen (CEA) levels (<1.0 ng/ml) but elevated CA 125 levels. Treatment of the metastatic disease with chemotherapy, plus surgery in one case, led to declines in the CA 125 levels. These decreases were associated with tumor regression, as confirmed by clinical and radiologic evidence. These findings lead us to conclude that the measurement of CA 125 for patients with normal CEA levels is useful in the management of colorectal carcinoma.

Original language	English (US)
Pages (from-to)	213-215
Number of pages	3
Journal	American Journal of Clinical Oncology: Cancer Clinical Trials
Volume	23
Issue number	2
DOIs	https://doi.org/10.1097/00000421-200004000-00021
State	Published - 2000

Keywords

CA 125
Carcinoembryonic antigen
Metastatic colorectal cancer

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1097/00000421-200004000-00021

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CA 125: A clinically useful tumor marker in the management of colorectal carcinoma metastatic to the liver in patients with normal carcinoembryonic antigen. / Mavligit, Giora M.; Estrov, Zeev; Buzdar, Aman U. et al.
In: American Journal of Clinical Oncology: Cancer Clinical Trials, Vol. 23, No. 2, 2000, p. 213-215.

Research output: Contribution to journal › Article › peer-review

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abstract = "Two patients with colon carcinoma metastatic to the liver had normal plasma carcinoembryonic antigen (CEA) levels (<1.0 ng/ml) but elevated CA 125 levels. Treatment of the metastatic disease with chemotherapy, plus surgery in one case, led to declines in the CA 125 levels. These decreases were associated with tumor regression, as confirmed by clinical and radiologic evidence. These findings lead us to conclude that the measurement of CA 125 for patients with normal CEA levels is useful in the management of colorectal carcinoma.",

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AU - Wogan, Christine F.

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AB - Two patients with colon carcinoma metastatic to the liver had normal plasma carcinoembryonic antigen (CEA) levels (<1.0 ng/ml) but elevated CA 125 levels. Treatment of the metastatic disease with chemotherapy, plus surgery in one case, led to declines in the CA 125 levels. These decreases were associated with tumor regression, as confirmed by clinical and radiologic evidence. These findings lead us to conclude that the measurement of CA 125 for patients with normal CEA levels is useful in the management of colorectal carcinoma.

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CA 125: A clinically useful tumor marker in the management of colorectal carcinoma metastatic to the liver in patients with normal carcinoembryonic antigen

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