Cancer immunology and the evolution of immunotherapy

Roza Nurieva; Margarita Divenko; Sang Kim

doi:10.1007/978-3-030-56824-5_1

Cancer immunology and the evolution of immunotherapy

Roza Nurieva, Margarita Divenko, Sang Kim

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Detailed understanding of molecular and cellular mechanisms of interactions between host immune cells and cancer cells led us to the development of cancer immunotherapeutics, one of the greatest achievements in the life sciences. In this chapter, we review how tumor cells acquire resistance to host anti-tumor immunity and the cancer immunotherapy modalities approved by the FDA or in preclinical studies/clinical trials. Finally, we discuss the future of cancer immunotherapy.

Original language	English (US)
Title of host publication	Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy
Subtitle of host publication	A Handbook for Diagnosis and Management
Publisher	Springer International Publishing
Pages	3-29
Number of pages	27
ISBN (Electronic)	9783030568245
ISBN (Print)	9783030568238
DOIs	https://doi.org/10.1007/978-3-030-56824-5_1
State	Published - Feb 16 2021

Keywords

Anti-tumor immunity
Cancer immunoediting
Cancer immunotherapy
Immune checkpoint inhibitors
T cells

ASJC Scopus subject areas

General Medicine
General Immunology and Microbiology

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10.1007/978-3-030-56824-5_1

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AB - Detailed understanding of molecular and cellular mechanisms of interactions between host immune cells and cancer cells led us to the development of cancer immunotherapeutics, one of the greatest achievements in the life sciences. In this chapter, we review how tumor cells acquire resistance to host anti-tumor immunity and the cancer immunotherapy modalities approved by the FDA or in preclinical studies/clinical trials. Finally, we discuss the future of cancer immunotherapy.

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KW - Cancer immunoediting

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KW - Immune checkpoint inhibitors

KW - T cells

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Cancer immunology and the evolution of immunotherapy

Abstract

Keywords

ASJC Scopus subject areas

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