Cancer radiotherapy: General considerations and human radiobiology

Alison K. Yoder; Matthew S. Ning; Melissa M. Joyner; Lilie L. Lin

doi:10.1007/978-3-030-56267-0_3

Cancer radiotherapy: General considerations and human radiobiology

Alison K. Yoder, Matthew S. Ning, Melissa M. Joyner, Lilie L. Lin

Radiation Oncology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Advancements in oncologic therapies have led to increasing numbers of long-term cancer survivors and thus more patients for whom radiation therapy is indicated as part of their comprehensive treatment plan. Here we provide an overview of the biologic mechanisms underlying radiation therapy, before examining the various radiotherapy modalities currently available in clinical practice, including modern innovations such as stereotactic ablative techniques, advanced image guidance, and proton beam therapy. We also discuss an exciting, relatively novel indication for radiation therapy that holds promise for improving patient outcomes and further expanding the field of radiotherapy: local consolidation in the definitive management of oligometastatic disease.

Original language	English (US)
Title of host publication	Locoregional Radionuclide Cancer Therapy
Subtitle of host publication	Clinical and Scientific Aspects
Publisher	Springer International Publishing
Pages	39-59
Number of pages	21
ISBN (Electronic)	9783030562670
ISBN (Print)	9783030562663
DOIs	https://doi.org/10.1007/978-3-030-56267-0_3
State	Published - Dec 8 2020

Keywords

Adaptive radiation therapy
Brachytherapy
External beam radiation therapy
Image-guided radiation therapy
Oligometastatic disease
Proton beam therapy
Radiosurgery
Stereotactic ablative radiation therapy

ASJC Scopus subject areas

General Medicine
General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1007/978-3-030-56267-0_3

Cite this

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abstract = "Advancements in oncologic therapies have led to increasing numbers of long-term cancer survivors and thus more patients for whom radiation therapy is indicated as part of their comprehensive treatment plan. Here we provide an overview of the biologic mechanisms underlying radiation therapy, before examining the various radiotherapy modalities currently available in clinical practice, including modern innovations such as stereotactic ablative techniques, advanced image guidance, and proton beam therapy. We also discuss an exciting, relatively novel indication for radiation therapy that holds promise for improving patient outcomes and further expanding the field of radiotherapy: local consolidation in the definitive management of oligometastatic disease.",

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AU - Yoder, Alison K.

AU - Ning, Matthew S.

AU - Joyner, Melissa M.

AU - Lin, Lilie L.

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Y1 - 2020/12/8

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AB - Advancements in oncologic therapies have led to increasing numbers of long-term cancer survivors and thus more patients for whom radiation therapy is indicated as part of their comprehensive treatment plan. Here we provide an overview of the biologic mechanisms underlying radiation therapy, before examining the various radiotherapy modalities currently available in clinical practice, including modern innovations such as stereotactic ablative techniques, advanced image guidance, and proton beam therapy. We also discuss an exciting, relatively novel indication for radiation therapy that holds promise for improving patient outcomes and further expanding the field of radiotherapy: local consolidation in the definitive management of oligometastatic disease.

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KW - Brachytherapy

KW - External beam radiation therapy

KW - Image-guided radiation therapy

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KW - Proton beam therapy

KW - Radiosurgery

KW - Stereotactic ablative radiation therapy

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Cancer radiotherapy: General considerations and human radiobiology

Abstract

Keywords

ASJC Scopus subject areas

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