TY - JOUR
T1 - Canine transmissible venereal tumor
T2 - A large-animal transplantable tumor model
AU - Rivera, Belinda
AU - Ahrar, Kamran
AU - Kangasniemi, Marko M.
AU - Hazle, John D.
AU - Price, Roger E.
PY - 2005
Y1 - 2005
N2 - The canine transplantable venereal tumor is a naturally occurring transplantable round-cell tumor in dogs. Although experimental transplantable tumor models in rodents and rabbits are readily available, a reliable transplantable tumor model in a large animal that more closely resembles the physical dimensions of humans has not been available. A tumor model in a large animal would have a wide range of biomedical research applications, including the study of various interventional imaging techniques. In this report, we characterize the experimental transplantation of the canine transmissible venereal tumor in the brain, skin, muscle, prostate, lung, liver, and bone of dogs and provide X-ray computed tomographic and magnetic resonance imaging characteristics of the tumors in the brain, muscle, lung, and prostate.
AB - The canine transplantable venereal tumor is a naturally occurring transplantable round-cell tumor in dogs. Although experimental transplantable tumor models in rodents and rabbits are readily available, a reliable transplantable tumor model in a large animal that more closely resembles the physical dimensions of humans has not been available. A tumor model in a large animal would have a wide range of biomedical research applications, including the study of various interventional imaging techniques. In this report, we characterize the experimental transplantation of the canine transmissible venereal tumor in the brain, skin, muscle, prostate, lung, liver, and bone of dogs and provide X-ray computed tomographic and magnetic resonance imaging characteristics of the tumors in the brain, muscle, lung, and prostate.
UR - http://www.scopus.com/inward/record.url?scp=33645962524&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645962524&partnerID=8YFLogxK
M3 - Article
C2 - 16158909
AN - SCOPUS:33645962524
SN - 1532-0820
VL - 55
SP - 335
EP - 343
JO - Comparative medicine
JF - Comparative medicine
IS - 4
ER -