Carcinoid Heart Disease: a Comprehensive Review

Saamir A. Hassan; Nicolas L. Palaskas; Ali M. Agha; Cezar Iliescu; Juan Lopez-Mattei; Christopher Chen; Henry Zheng; Syed Wamique Yusuf

doi:10.1007/s11886-019-1207-8

Carcinoid Heart Disease: a Comprehensive Review

Saamir A. Hassan, Nicolas L. Palaskas, Ali M. Agha, Cezar Iliescu, Juan Lopez-Mattei, Christopher Chen, Henry Zheng, Syed Wamique Yusuf

Cardiology

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Purpose of Review: Carcinoid heart disease is a rare disorder that is associated with significant morbidity and mortality. In this review of the literature, we will present current concepts in diagnosis and management of carcinoid heart disease. Recent Findings: Recent expert consensus guidelines highlight the role of echocardiography and screening with NT-proBNP for the evaluation of carcinoid heart disease. Advances in medical therapy along with better surgical outcomes highlight the experience and expertise that has been gained in the treatment of carcinoid heart disease. Summary: Carcinoid heart disease occurs in patients with neuroendocrine tumors who have carcinoid syndrome. Serotonin appears to play a central role in the development of carcinoid heart disease. Cardiac biomarkers and multimodality imaging can be used to aid in screening and diagnosis. The mainstay of treatment of carcinoid heart disease is surgery.

Original language	English (US)
Article number	140
Journal	Current Cardiology Reports
Volume	21
Issue number	11
DOIs	https://doi.org/10.1007/s11886-019-1207-8
State	Published - Nov 1 2019

Keywords

Carcinoid heart disease
Multimodality imaging

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1007/s11886-019-1207-8

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title = "Carcinoid Heart Disease: a Comprehensive Review",

abstract = "Purpose of Review: Carcinoid heart disease is a rare disorder that is associated with significant morbidity and mortality. In this review of the literature, we will present current concepts in diagnosis and management of carcinoid heart disease. Recent Findings: Recent expert consensus guidelines highlight the role of echocardiography and screening with NT-proBNP for the evaluation of carcinoid heart disease. Advances in medical therapy along with better surgical outcomes highlight the experience and expertise that has been gained in the treatment of carcinoid heart disease. Summary: Carcinoid heart disease occurs in patients with neuroendocrine tumors who have carcinoid syndrome. Serotonin appears to play a central role in the development of carcinoid heart disease. Cardiac biomarkers and multimodality imaging can be used to aid in screening and diagnosis. The mainstay of treatment of carcinoid heart disease is surgery.",

keywords = "Carcinoid heart disease, Multimodality imaging",

author = "Hassan, {Saamir A.} and Palaskas, {Nicolas L.} and Agha, {Ali M.} and Cezar Iliescu and Juan Lopez-Mattei and Christopher Chen and Henry Zheng and Yusuf, {Syed Wamique}",

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doi = "10.1007/s11886-019-1207-8",

language = "English (US)",

volume = "21",

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T2 - a Comprehensive Review

AU - Hassan, Saamir A.

AU - Palaskas, Nicolas L.

AU - Agha, Ali M.

AU - Iliescu, Cezar

AU - Lopez-Mattei, Juan

AU - Chen, Christopher

AU - Zheng, Henry

AU - Yusuf, Syed Wamique

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Purpose of Review: Carcinoid heart disease is a rare disorder that is associated with significant morbidity and mortality. In this review of the literature, we will present current concepts in diagnosis and management of carcinoid heart disease. Recent Findings: Recent expert consensus guidelines highlight the role of echocardiography and screening with NT-proBNP for the evaluation of carcinoid heart disease. Advances in medical therapy along with better surgical outcomes highlight the experience and expertise that has been gained in the treatment of carcinoid heart disease. Summary: Carcinoid heart disease occurs in patients with neuroendocrine tumors who have carcinoid syndrome. Serotonin appears to play a central role in the development of carcinoid heart disease. Cardiac biomarkers and multimodality imaging can be used to aid in screening and diagnosis. The mainstay of treatment of carcinoid heart disease is surgery.

AB - Purpose of Review: Carcinoid heart disease is a rare disorder that is associated with significant morbidity and mortality. In this review of the literature, we will present current concepts in diagnosis and management of carcinoid heart disease. Recent Findings: Recent expert consensus guidelines highlight the role of echocardiography and screening with NT-proBNP for the evaluation of carcinoid heart disease. Advances in medical therapy along with better surgical outcomes highlight the experience and expertise that has been gained in the treatment of carcinoid heart disease. Summary: Carcinoid heart disease occurs in patients with neuroendocrine tumors who have carcinoid syndrome. Serotonin appears to play a central role in the development of carcinoid heart disease. Cardiac biomarkers and multimodality imaging can be used to aid in screening and diagnosis. The mainstay of treatment of carcinoid heart disease is surgery.

KW - Carcinoid heart disease

KW - Multimodality imaging

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Carcinoid Heart Disease: a Comprehensive Review

Abstract

Keywords

ASJC Scopus subject areas

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