TY - JOUR
T1 - Cardiac manifestations in dermato-polymyositis
AU - Gonzalez-Lopez, L.
AU - Gamez-Nava, J. I.
AU - Sanchez, L.
AU - Rosas, E.
AU - Suarez-Almazor, M.
AU - Cardona-Muñoz, E.
AU - Ramos-Remus, C.
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 1996/7
Y1 - 1996/7
N2 - Objective. To describe the functional and anatomic heart abnormalities of patients with dermatopolymyositis. Methods. Thirty-two consecutive patients with dermato-polymyositis (DM/PM) were sludied. Patient assessments included a questionnaire for cardiac symptoms, physical examination, muscular enzymes, standard electrocardiogram (ECG), chest radiographs, spirometry, Holter monitoring and color Doppler flow (CDF) studies. Features evaluated with CDF included left ventricular diastolic dysfunction (LVDD), hyperdynamic heart, mitral valve prolapse, and endomyocardial fibrosis. Results. Twenty-five patients (78%) were female. The mean age was 43 years and the mean disease duration 6 years. Twenty-six (81%) patients had dermtomyositis. Only 2 (6%) had cardiac symptoms. Spirometry was performed in 20 patients, Holter monitoring in 23 and CDF in 26 patients. Electrical disturbances detected by either ECG or Holter were present in more than half of the patients studied. EVDD was identified in 11 patients (42%) and hyperdynamic heart in 4 (15%). None of the 26 patients studied by CDF had mitral valve prolapse. No significant differences in the frequency of cardiac abnormalities, including LVDD, were observed in relation to the diagnosis of DM or PM, the presence of Raynaud's phenomenon or calcinosis, or the disease activity status at the moment of the study. Conclusions. Subclinical heart abnormalities are frequent in patients with DM/PM. LVDD appears to be common. Our flndings suggest that cardial assessment of patients should be performed in order to detect abnormalities requiring specific therapy.
AB - Objective. To describe the functional and anatomic heart abnormalities of patients with dermatopolymyositis. Methods. Thirty-two consecutive patients with dermato-polymyositis (DM/PM) were sludied. Patient assessments included a questionnaire for cardiac symptoms, physical examination, muscular enzymes, standard electrocardiogram (ECG), chest radiographs, spirometry, Holter monitoring and color Doppler flow (CDF) studies. Features evaluated with CDF included left ventricular diastolic dysfunction (LVDD), hyperdynamic heart, mitral valve prolapse, and endomyocardial fibrosis. Results. Twenty-five patients (78%) were female. The mean age was 43 years and the mean disease duration 6 years. Twenty-six (81%) patients had dermtomyositis. Only 2 (6%) had cardiac symptoms. Spirometry was performed in 20 patients, Holter monitoring in 23 and CDF in 26 patients. Electrical disturbances detected by either ECG or Holter were present in more than half of the patients studied. EVDD was identified in 11 patients (42%) and hyperdynamic heart in 4 (15%). None of the 26 patients studied by CDF had mitral valve prolapse. No significant differences in the frequency of cardiac abnormalities, including LVDD, were observed in relation to the diagnosis of DM or PM, the presence of Raynaud's phenomenon or calcinosis, or the disease activity status at the moment of the study. Conclusions. Subclinical heart abnormalities are frequent in patients with DM/PM. LVDD appears to be common. Our flndings suggest that cardial assessment of patients should be performed in order to detect abnormalities requiring specific therapy.
KW - cardiac manifestations
KW - dermatomyositis
KW - myopathy
KW - polymyositis
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M3 - Article
C2 - 8871835
AN - SCOPUS:0030057878
SN - 0392-856X
VL - 14
SP - 373
EP - 379
JO - Clinical and experimental rheumatology
JF - Clinical and experimental rheumatology
IS - 4
ER -