Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations

Denise R. Nebgen; Susan M. Domchek; Joanne Kotsopoulos; Joanne A. de Hullu; Emma J. Crosbie; Vincent Singh Paramanandam; Monique M.A. Brood - van Zanten; Barbara M. Norquist; Theresa Guise; Serge Rozenberg; Allison W. Kurian; Holly J. Pederson; Nese Yuksel; Rachel Michaelson-Cohen; Sharon L. Bober; Agnaldo Lopes da Silva Filho; Nora Johansen; F. Guidozzi; D. Gareth Evans; Usha Menon; Sheryl A. Kingsberg; C. Bethan Powell; Giovanni Grandi; Claudia Marchetti; Michelle Jacobson; Donal J. Brennan; Martha Hickey

doi:10.1111/1471-0528.17511

Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations

Denise R. Nebgen, Susan M. Domchek, Joanne Kotsopoulos, Joanne A. de Hullu, Emma J. Crosbie, Vincent Singh Paramanandam, Monique M.A. Brood - van Zanten, Barbara M. Norquist, Theresa Guise, Serge Rozenberg, Allison W. Kurian, Holly J. Pederson, Nese Yuksel, Rachel Michaelson-Cohen, Sharon L. Bober, Agnaldo Lopes da Silva Filho, Nora Johansen, F. Guidozzi, D. Gareth Evans, Usha MenonSheryl A. Kingsberg, C. Bethan Powell, Giovanni Grandi, Claudia Marchetti, Michelle Jacobson, Donal J. Brennan, Martha Hickey

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.

Original language	English (US)
Pages (from-to)	1437-1450
Number of pages	14
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	130
Issue number	12
DOIs	https://doi.org/10.1111/1471-0528.17511
State	Published - Nov 2023

Keywords

BRCA1
BRCA2
early menopause
hormone replacement therapy
hot flushes
ovarian cancer
risk-reducing salpingo-oophorectomy
sexual function
surgical menopause

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1111/1471-0528.17511

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Nebgen, D. R., Domchek, S. M., Kotsopoulos, J., de Hullu, J. A., Crosbie, E. J., Paramanandam, V. S., Brood - van Zanten, M. M. A., Norquist, B. M., Guise, T., Rozenberg, S., Kurian, A. W., Pederson, H. J., Yuksel, N., Michaelson-Cohen, R., Bober, S. L., da Silva Filho, A. L., Johansen, N., Guidozzi, F., Evans, D. G., ... Hickey, M. (2023). Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations. BJOG: An International Journal of Obstetrics and Gynaecology, 130(12), 1437-1450. https://doi.org/10.1111/1471-0528.17511

Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations. / Nebgen, Denise R.; Domchek, Susan M.; Kotsopoulos, Joanne et al.
In: BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 130, No. 12, 11.2023, p. 1437-1450.

Research output: Contribution to journal › Review article › peer-review

Nebgen, DR, Domchek, SM, Kotsopoulos, J, de Hullu, JA, Crosbie, EJ, Paramanandam, VS, Brood - van Zanten, MMA, Norquist, BM, Guise, T, Rozenberg, S, Kurian, AW, Pederson, HJ, Yuksel, N, Michaelson-Cohen, R, Bober, SL, da Silva Filho, AL, Johansen, N, Guidozzi, F, Evans, DG, Menon, U, Kingsberg, SA, Powell, CB, Grandi, G, Marchetti, C, Jacobson, M, Brennan, DJ & Hickey, M 2023, 'Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 130, no. 12, pp. 1437-1450. https://doi.org/10.1111/1471-0528.17511

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title = "Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations",

abstract = "Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.",

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author = "Nebgen, {Denise R.} and Domchek, {Susan M.} and Joanne Kotsopoulos and {de Hullu}, {Joanne A.} and Crosbie, {Emma J.} and Paramanandam, {Vincent Singh} and {Brood - van Zanten}, {Monique M.A.} and Norquist, {Barbara M.} and Theresa Guise and Serge Rozenberg and Kurian, {Allison W.} and Pederson, {Holly J.} and Nese Yuksel and Rachel Michaelson-Cohen and Bober, {Sharon L.} and {da Silva Filho}, {Agnaldo Lopes} and Nora Johansen and F. Guidozzi and Evans, {D. Gareth} and Usha Menon and Kingsberg, {Sheryl A.} and Powell, {C. Bethan} and Giovanni Grandi and Claudia Marchetti and Michelle Jacobson and Brennan, {Donal J.} and Martha Hickey",

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Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations

Abstract

Keywords

ASJC Scopus subject areas

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