TY - JOUR
T1 - Case-control comparison of quality of life in long-term ovarian germ cell tumor survivors
T2 - A gynecologic oncology group study
AU - Monahan, Patrick O.
AU - Champion, Victoria L.
AU - Zhao, Qianqian
AU - Miller, Anna M.
AU - Gershenson, David
AU - Williams, Stephen D.
AU - Cella, David
N1 - Funding Information:
This study was supported by National Cancer Institute R01 grant CA77470 and the NCI grants to the Gynecologic Oncology Group Administrative Office (CA 27469) and the Gynecologic Oncology Group Statistical Office (CA 37517). The following Gynecologic Oncology Group member institutions participated in this study: University of Alabama at Birmingham; Duke University Medical Center; Abington Memorial Hospital; University of Minnesota Medical School; University of Mississippi Medical Center; Colorado Gynecologic Oncology Group P.C.; Milton S. Hershey Medical Center; University of Cincinnati; University of North Carolina School of Medicine; University of Iowa Hospitals and Clinics; Indiana University School of Medicine; Wake Forest University School of Medicine; University of California Medical Center at Irvine; Tufts-New England Medical Center; Rush-Presbyterian–St. Luke’s Medical Center; SUNY Downstate Medical Center; University of Kentucky; Community Clinical Oncology Program; The Cleveland Clinic Foundation; Johns Hopkins Oncology Center; State University of New York at Stony Brook; Eastern Pennsylvania GYN/ONC Center, P.D.; Washington University School of Medicine; Memorial Sloan-Kettering Cancer Center; Cooper Hospital/University Medical Center; Columbus Cancer Council; Fox Chase Cancer Center; University of Oklahoma; Tacoma General Hospital; Christiana Health Care; Carolinas Medical Care Center; Grant/Riverside Cancer Services; Hinsdale Hospital; Massachusetts General Hospital; Long Beach Memorial Medical Center; Miami Valley Hospital; University of New Mexico; University of Wisconsin; Women & Infants Hospital of Rhode Island; Women’s Hospital, Baton Rouge.
PY - 2008/6/16
Y1 - 2008/6/16
N2 - Ovarian germ cell cancer is a rare tumor. Approximately 1000 to 2000 women in the United States will be diagnosed with ovarian germ cell cancer in 2007. When it occurs, it is usually diagnosed before age 20 and is highly responsive to therapy. Most patients live a full life span. The 5-year relative survival rate is 95%. This article describes differences in quality of life issues between ovarian germ cell cancer survivors and young women who have not experienced cancer and were matched to survivors on age, education, and race (by the acquaintance control method). Survivors and controls completed mail and phone surveys. A multivariable logistic regression model was adjusted for age, education, household income, marital status, and perception of fertility. Compared to controls, germ cell cancer survivors expressed more reproductive concerns and reported worse sexual functioning, but they also experienced greater appreciation of life and more affective (i.e., emotional) social support. Future research is suggested to test interventions to enhance quality of life for ovarian germ cell cancer survivors in the areas of sexual functioning and reproductive concerns, but only for survivors who are in distress or in need of the support. Potential screening questions are offered for clinicians, but further research is needed to assess their validity as screening tools.
AB - Ovarian germ cell cancer is a rare tumor. Approximately 1000 to 2000 women in the United States will be diagnosed with ovarian germ cell cancer in 2007. When it occurs, it is usually diagnosed before age 20 and is highly responsive to therapy. Most patients live a full life span. The 5-year relative survival rate is 95%. This article describes differences in quality of life issues between ovarian germ cell cancer survivors and young women who have not experienced cancer and were matched to survivors on age, education, and race (by the acquaintance control method). Survivors and controls completed mail and phone surveys. A multivariable logistic regression model was adjusted for age, education, household income, marital status, and perception of fertility. Compared to controls, germ cell cancer survivors expressed more reproductive concerns and reported worse sexual functioning, but they also experienced greater appreciation of life and more affective (i.e., emotional) social support. Future research is suggested to test interventions to enhance quality of life for ovarian germ cell cancer survivors in the areas of sexual functioning and reproductive concerns, but only for survivors who are in distress or in need of the support. Potential screening questions are offered for clinicians, but further research is needed to assess their validity as screening tools.
KW - Case-control
KW - Long-term cancer survivors
KW - Ovarian germ cell cancer
KW - Quality of life
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U2 - 10.1080/07347330802115715
DO - 10.1080/07347330802115715
M3 - Article
C2 - 19042263
AN - SCOPUS:65749300163
SN - 0734-7332
VL - 26
SP - 19
EP - 42
JO - Journal of Psychosocial Oncology
JF - Journal of Psychosocial Oncology
IS - 3
ER -