TY - JOUR
T1 - Case reports
T2 - treatment of nevirapine-associated dress syndrome with intravenous immune globulin (IVIG).
AU - Fields, Katherine S.
AU - Petersen, Marta J.
AU - Chiao, Elizabeth
AU - Tristani-Firouzi, Payam
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2005
Y1 - 2005
N2 - Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an adverse drug reaction most commonly associated with aromatic antiepileptic agents. It is characterized by the triad of skin eruption, fever, and systemic involvement, with the latter usually manifesting as hepatitis and lymphadenopathy. Mortality is primarily due to hepatic failure and can be as high as 10%. Formerly referred to by names such as Dilantin hypersensitivity syndrome and anticonvulsant hypersensitivity syndrome, DRESS syndrome is a more precise term since this reaction pattern can be seen with other agents. DRESS syndrome has also been reported in association with sulfonamides, allopurinol, terbinafine, minocycline, azathioprine, and dapsone as well as with several antiretroviral agents such as abacavir and nevirapine. We describe a patient with HIV who developed nevirapine hypersensitivity syndrome who was successfully treated with intravenous immune globulin (IVIG).
AB - Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an adverse drug reaction most commonly associated with aromatic antiepileptic agents. It is characterized by the triad of skin eruption, fever, and systemic involvement, with the latter usually manifesting as hepatitis and lymphadenopathy. Mortality is primarily due to hepatic failure and can be as high as 10%. Formerly referred to by names such as Dilantin hypersensitivity syndrome and anticonvulsant hypersensitivity syndrome, DRESS syndrome is a more precise term since this reaction pattern can be seen with other agents. DRESS syndrome has also been reported in association with sulfonamides, allopurinol, terbinafine, minocycline, azathioprine, and dapsone as well as with several antiretroviral agents such as abacavir and nevirapine. We describe a patient with HIV who developed nevirapine hypersensitivity syndrome who was successfully treated with intravenous immune globulin (IVIG).
UR - http://www.scopus.com/inward/record.url?scp=33644698765&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33644698765&partnerID=8YFLogxK
M3 - Article
C2 - 16004028
AN - SCOPUS:33644698765
SN - 1545-9616
VL - 4
SP - 510
EP - 513
JO - Journal of drugs in dermatology : JDD
JF - Journal of drugs in dermatology : JDD
IS - 4
ER -