Abstract
Among the membrane compartments of a cell, vesicles known as "caveolae" have long defied functional characterization. However, since the identification of a family of proteins termed "caveolins", that form and reside in caveolae, a better understanding has emerged. It is now clear that caveolae do not merely play a singular role in the cell, but are pleiotropic in nature - serving to modulate many cellular functions. The purpose of this review is to explicate what is known about caveolins/caveolae and highlight growing areas of caveolar research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 431-467 |
| Number of pages | 37 |
| Journal | Pharmacological Reviews |
| Volume | 54 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 2002 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology