Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis

Charlotte R. Hawkey, Timothy Yap, Janis Pereira, David A.J. Moore, Robert N. Davidson, Geoffrey Pasvol, Min Kon Onn, Robert A. Wall, Robert J. Wilkinson

Research output: Contribution to journalArticlepeer-review

132 Scopus citations

Abstract

In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus-uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21-139 days) and persisting for a median of 67.5 days (interquartile range, 34-111 days). We found no association between the use of steroids and the duration of reaction.

Original languageEnglish (US)
Pages (from-to)1368-1371
Number of pages4
JournalClinical Infectious Diseases
Volume40
Issue number9
DOIs
StatePublished - May 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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