Characterization of laser-induced thermal response of nanoshells for cancer treatment using magnetic-resonance temperature imaging

Andrew M. Elliott, R. Jason Stafford, Jon Schwartz, James Wang, Anil M. Shetty, Chris Bourgoyne, D. Patrick O'Neal, John D. Hazle

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Laser induced thermal therapy is used in conjunction with gold coated silica core nanoshells and magneticresonance temperature imaging (MRTI). The nanoshells are embedded in phantom or in vivo tumors and heat preferentially compared to surrounding tissue when the laser is applied. The tissues thermal response is varied by either the laser power or the nanoshell concentration. In this way precise control of the heating can be achieved. This results in the ability to quantitatively monitor therapeutic temperature changes that occur in a spatiotemporally controlled way. This provides an unprecedented means proscribing and monitoring a treatment in real time and the ability to make precise corrections when necessary.

Original languageEnglish (US)
Title of host publicationThermal Treatment of Tissue
Subtitle of host publicationEnergy Delivery and Assessment IV
DOIs
StatePublished - 2007
EventThermal Treatment of Tissue: Energy Delivery and Assessment IV - San Jose, CA, United States
Duration: Jan 20 2007Jan 21 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6440
ISSN (Print)1605-7422

Other

OtherThermal Treatment of Tissue: Energy Delivery and Assessment IV
Country/TerritoryUnited States
CitySan Jose, CA
Period1/20/071/21/07

Keywords

  • Auroshells
  • Cancer therapy
  • LITT
  • Numerical model
  • Thermal response

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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