Chemotherapy in combination with resection for colorectal liver metastases – current evidence

Maciej Krasnodebski; Bradford J. Kim; Steven H. Wei; Jenilette D. Velasco; Yujiro Nishioka; Jean Nicolas Vauthey

doi:10.1016/j.sipas.2020.100021

Chemotherapy in combination with resection for colorectal liver metastases – current evidence

Maciej Krasnodebski, Bradford J. Kim, Steven H. Wei, Jenilette D. Velasco, Yujiro Nishioka, Jean Nicolas Vauthey

Surgical Oncology

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Colorectal liver metastasis (CLM) occurs in a significant number of patients with colorectal cancer. Over several decades, surgical methods and chemotherapy improved, making it possible to extend the life of CLM patients. Currently, the multitude of treatment options and sequences make it challenging to choose the most appropriate regimen for each patient. The current review is based on available randomized trials, other impactful studies, and several national guidelines regarding chemotherapy and surgery for CLM patients. Amid the options available, it is necessary to emphasize the still dominant role of surgery in the treatment of CLM. Moreover, a multidisciplinary team approach is required to develop the best surgical and systemic treatment plans for the many CLM patients that do not fall under general guidelines.

Original language	English (US)
Article number	100021
Journal	Surgery in Practice and Science
Volume	3
DOIs	https://doi.org/10.1016/j.sipas.2020.100021
State	Published - Dec 2020

Keywords

Chemotherapy
Colorectal liver metastases
Liver resection

ASJC Scopus subject areas

Surgery
Urology
Otorhinolaryngology

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10.1016/j.sipas.2020.100021

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@article{f190462c8d5a486e8645bf85fac3cc29,

title = "Chemotherapy in combination with resection for colorectal liver metastases – current evidence",

abstract = "Colorectal liver metastasis (CLM) occurs in a significant number of patients with colorectal cancer. Over several decades, surgical methods and chemotherapy improved, making it possible to extend the life of CLM patients. Currently, the multitude of treatment options and sequences make it challenging to choose the most appropriate regimen for each patient. The current review is based on available randomized trials, other impactful studies, and several national guidelines regarding chemotherapy and surgery for CLM patients. Amid the options available, it is necessary to emphasize the still dominant role of surgery in the treatment of CLM. Moreover, a multidisciplinary team approach is required to develop the best surgical and systemic treatment plans for the many CLM patients that do not fall under general guidelines.",

keywords = "Chemotherapy, Colorectal liver metastases, Liver resection",

author = "Maciej Krasnodebski and Kim, {Bradford J.} and Wei, {Steven H.} and Velasco, {Jenilette D.} and Yujiro Nishioka and Vauthey, {Jean Nicolas}",

note = "Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = dec,

doi = "10.1016/j.sipas.2020.100021",

language = "English (US)",

volume = "3",

journal = "Surgery in Practice and Science",

issn = "2666-2620",

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TY - JOUR

T1 - Chemotherapy in combination with resection for colorectal liver metastases – current evidence

AU - Krasnodebski, Maciej

AU - Kim, Bradford J.

AU - Wei, Steven H.

AU - Velasco, Jenilette D.

AU - Nishioka, Yujiro

AU - Vauthey, Jean Nicolas

PY - 2020/12

Y1 - 2020/12

N2 - Colorectal liver metastasis (CLM) occurs in a significant number of patients with colorectal cancer. Over several decades, surgical methods and chemotherapy improved, making it possible to extend the life of CLM patients. Currently, the multitude of treatment options and sequences make it challenging to choose the most appropriate regimen for each patient. The current review is based on available randomized trials, other impactful studies, and several national guidelines regarding chemotherapy and surgery for CLM patients. Amid the options available, it is necessary to emphasize the still dominant role of surgery in the treatment of CLM. Moreover, a multidisciplinary team approach is required to develop the best surgical and systemic treatment plans for the many CLM patients that do not fall under general guidelines.

AB - Colorectal liver metastasis (CLM) occurs in a significant number of patients with colorectal cancer. Over several decades, surgical methods and chemotherapy improved, making it possible to extend the life of CLM patients. Currently, the multitude of treatment options and sequences make it challenging to choose the most appropriate regimen for each patient. The current review is based on available randomized trials, other impactful studies, and several national guidelines regarding chemotherapy and surgery for CLM patients. Amid the options available, it is necessary to emphasize the still dominant role of surgery in the treatment of CLM. Moreover, a multidisciplinary team approach is required to develop the best surgical and systemic treatment plans for the many CLM patients that do not fall under general guidelines.

KW - Chemotherapy

KW - Colorectal liver metastases

KW - Liver resection

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DO - 10.1016/j.sipas.2020.100021

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VL - 3

JO - Surgery in Practice and Science

JF - Surgery in Practice and Science

M1 - 100021

ER -

Chemotherapy in combination with resection for colorectal liver metastases – current evidence

Abstract

Keywords

ASJC Scopus subject areas

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