TY - JOUR
T1 - Chromatin-mediated transcription repression in yeast
AU - Roth, Sharon Y.
N1 - Funding Information:
I thank Diane Edmondson and David Roth for critical reading of the manuscript and helpful suggestions. I acknowledge support from the Texas Advanced Research Program and the National Institutes of Health. I apologize to the many colleagues whose work I could not reference directly because of space limitations.
PY - 1995/4
Y1 - 1995/4
N2 - Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and α2.
AB - Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and α2.
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U2 - 10.1016/0959-437X(95)80004-2
DO - 10.1016/0959-437X(95)80004-2
M3 - Article
C2 - 7613085
AN - SCOPUS:0028906077
SN - 0959-437X
VL - 5
SP - 168
EP - 173
JO - Current Opinion in Genetics and Development
JF - Current Opinion in Genetics and Development
IS - 2
ER -