TY - JOUR
T1 - Chromosomal localization of the human annexin III (ANX3) gene
AU - Tait, Jonathan F.
AU - Frankenberry, D. Alan
AU - Miao, Carol H.
AU - Killary, Ann M.
AU - Adler, David A.
AU - Disteche, Christine M.
N1 - Funding Information:
We thank Christy Smith for help with some experiments, Don Gibson for oligonucleotide synthesis, Sheyla West for samples of human genomic DNA, and Dr. Jeffrey Murray for providing DNA from the HA(4)A cell line. This work was supported by NIH Grants HL-40801 (to J.F.T.), AG-01751 and March of Dimes l-1019 (to C.M.D.), and GM-37999 and HG-00042 (to A.M.K.).
PY - 1991/6
Y1 - 1991/6
N2 - The annexins or lipocortins are a new family of calcium-dependent phospholipid-binding proteins. Annexin III has been previously identified as inositol 1,2-cyclic phosphate 2-phosphohydrolase (EC 3.1.4.36), an enzyme of inositol phosphate metabolism, and also as placental anticoagulant protein III, lipocortin III, calcimedin 35-α, and an abundant neutrophil cytoplasmic protein. In this study, the gene (ANX3) encoding annexin III was localized to human chromosome 4 at band q21 (q13-q22) by (1) polymerase chain reaction analysis of a human-rodent hybrid cell panel, confirmed by genomic Southern blot analysis of the same panel with a cDNA probe and (2) in situ hybridization with a cDNA probe.
AB - The annexins or lipocortins are a new family of calcium-dependent phospholipid-binding proteins. Annexin III has been previously identified as inositol 1,2-cyclic phosphate 2-phosphohydrolase (EC 3.1.4.36), an enzyme of inositol phosphate metabolism, and also as placental anticoagulant protein III, lipocortin III, calcimedin 35-α, and an abundant neutrophil cytoplasmic protein. In this study, the gene (ANX3) encoding annexin III was localized to human chromosome 4 at band q21 (q13-q22) by (1) polymerase chain reaction analysis of a human-rodent hybrid cell panel, confirmed by genomic Southern blot analysis of the same panel with a cDNA probe and (2) in situ hybridization with a cDNA probe.
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U2 - 10.1016/0888-7543(91)90330-H
DO - 10.1016/0888-7543(91)90330-H
M3 - Article
C2 - 1830024
AN - SCOPUS:0026094536
SN - 0888-7543
VL - 10
SP - 441
EP - 448
JO - Genomics
JF - Genomics
IS - 2
ER -