Clinical and genetic features of human germ cell cancer

E. Dmitrovsky, G. J. Bosl, R. S.K. Chaganti

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

The majority of patients with disseminated germ cell cancer can be cured. However, subsets of these patients are either refractory to initial treatment or relapse after treatment. The management of these different clinical groups is reviewed. An enhanced understanding of the basic biological features of germ cell cancer may well lead to improvements in the management of this disease. Recent advances in the biological and genetic aspects of germ cell cancer which are pertinent to the behaviour of this malignancy are summarized.

Original languageEnglish (US)
Pages (from-to)369-386
Number of pages18
JournalCancer Surveys
Volume9
Issue number2
StatePublished - 1990

Keywords

  • Human germ cell cancer
  • Human teratocarcinoma Isochromosome 12p
  • Tumour differentiation

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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